Thursday, November 8th
Attendees will be able to participate in either Thursday event
Pre-Conference - Hormone Primer
HORMONE EVALUATION OF THE AGING MALE
The clinical syndrome related to the decline in testosterone, DHEA (-S) and testosterone-to-estradiol ration occurs in men gradually, beginning at approximately age 35. This session examines the relationship of testosterone and DHEA in men and discusses clinical interventions, risks and benefits.
Moderator- Robert D. Willix, Jr. M.D.
8:00am-8:45am
Testosterone Physiology and Measurement
Alvin B. Lin, M.D., FAAFP
Senior Physician, Cenegenics Medical Institute
Course Co-Director, Faculty, Cenegenics Education and Research Foundation (CERF)
Clinical Assistant Professor, Department Family and Community Medicine, University of Nevada School of Medicine
8:45am-9:15am
Relationship Between Testosterone, Libido and Erectile Quality
Alvin B. Lin, M.D., FAAFP
Senior Physician, Cenegenics Medical Institute
Course Co-Director, Faculty, Cenegenics Education and Research Foundation (CERF)
Clinical Assistant Professor, Department Family and Community Medicine, University of Nevada School of Medicine
9:15am-9:45am
Relationship between Testosterone, Cognitive Function and Mood
Alvin B. Lin, M.D., FAAFP
Senior Physician, Cenegenics Medical Institute
Course Co-Director, Faculty, Cenegenics Education and Research Foundation (CERF)
Clinical Assistant Professor, Department Family and Community Medicine, University of Nevada School of Medicine
9:45am-10:00am
Absolute and Relative Contraindications to Testosterone Replacement
Alvin B. Lin, M.D., FAAFP
Senior Physician, Cenegenics Medical Institute
Course Co-Director, Faculty, Cenegenics Education and Research Foundation (CERF)
Clinical Assistant Professor, Department Family and Community Medicine, University of Nevada School of Medicine
10:00-10:15pm Break
Moderator- Michale J. Barber, M.D.
10:15am-11:00am
Testosterone Replacement Dosing, Delivery Method and Treatment Goals
Jeffry S. Life, M.D., Ph.D.
Senior Physician, Cenegenics Medical Institute
11:00am-11:30am
Testosterone Replacement Therapy Concerns and Side Effects
Jeffry S. Life, M.D., Ph.D.
Senior Physician, Cenegenics Medical Institute
11:30am-12:00pm
DHEA (-S) Physiology, Measurement and Replacement
Jeffry S. Life, M.D., Ph.D.
Senior Physician, Cenegenics Medical Institute
12:00-1:15pm Lunch Break
HORMONE EVALUATION OF THE AGING FEMALE
The clinical syndrome related to the decline in estradiol and progesterone occurs in women beginning around their late 40s and early to mid-50s. This session examines menopause signs and symptoms, pathophysiology, clinical diagnosis and treatment. Ricks and benefits of bioidentical versus non-bioidentical hormone replacement therapy, various modes of administration and side effects are discussed.
Moderator- Joseph McWherter, M.D.
1:15-1:45pm
Estrogen Physiology and Measurement
Florence Comite, M.D.
Associate Clinical Professor, Yale University School of Medicine
1:45-2:15pm
Menopause
Florence Comite, M.D.
Associate Clinical Professor, Yale University School of Medicine
2:15-2:45pm
Relationship between Estrogen / Hormone Replacement Therapy (ERT / HRT) and Related Disease States
Florence Comite, M.D.
Associate Clinical Professor, Yale University School of Medicine
2:45-3:30pm
Estrogen Replacement Dosing, Delivery Method and Treatment Goals
Florence Comite, M.D.
Associate Clinical Professor, Yale University School of Medicine
3:30-3:45pm Break
_______________________________________________________________________
Moderator- Robert D. Willix, Jr. M.D
3:45-4:15pm
Absolute and Relative Contraindications to Estrogen Replacement Therapy / Hormone Replacement Therapy
and Alternative Therapies
Joseph McWherter, M.D.
Chairman, Conference Planning Committee Age Management Medicine Group
Editor, e-Journal of Age Management Medicine
4:15-4:45pm
Estrogen Replacement Therapy / Hormone Replacement Therapy Concerns and Side Effects
Joseph McWherter, M.D.
Chairman, Conference Planning Committee Age Management Medicine Group
Editor, e-Journal of Age Management Medicine
_______________________________________________________________________
4:45-5:15pm
Progesterone Physiology, Measurement and Replacement
Joseph McWherter, M.D.
Chairman, Conference Planning Committee, Age Management Medicine Group
Editor, e-Journal of Age Management Medicine
5:15-5:45pm
Session Q & A
Alvin Linn, M.D.
Jeffry S. Life, M.D., Ph.D.
Florence Comite, M.D.
Joseph McWherter, M.D.
Thursday, November 8th
Workshop Aesthetic Medicine
Please note that CME’s will not be offered for this workshop
8:00am-10:00am
Updated Laser Concepts Use and Application (Live Demonstrations)
Edward M. Zimmerman, M.D., P.C.
Private Practice, Las Vegas, NV
Combination light therapy with different wave lengths gives synergistic results with multiple treatments and less down time. Stacking technologies are now available from a single laser platform that provides results without increasing adverse effects.
Radio frequency energy to improve skin tightness, skin firmness, the appearance of cellulite and reduce body girth. A novel new method of RF delivery will be discussed which will revolutionize RF treatments in the USA. Fractional resurfacing will be presented that avoids the traditional pitfalls of ablative resurfacing such as the need for anesthesia, long recovery periods, permanent hypopigmentation and post-laser resurfacing erythema. Due to the low cost and risk, and simplicity that permits delegation, it will become the preferred method for textural improvement of the skin
10:00-10:15pm
Break
10:15am-11:45am
Medical Use and Understanding of Skin Rejuvenation Compounds & Ingredients - Protocols for Use
Sheila Malmanis, L.E.
CEO, MS Skintechnical, Inc.
Physicians and patients are bombarded with a wide array of skincare products, but what is actually in these compounds? What compounds or ingredients have clinical studies or an evidence basis for use and effectiveness? This non commercial lecture will discuss these issues and identify those compounds and ingredients which are effective and provide protocols for their use in an office based aesthetic practice.
11:45-1:00pm
Lunch Break
1:00-2:30pm
LED Light Therapy (Live Demonstrations)
Faculty TBD
LED Light Therapy - What is it? How does it work? How to make it work for you? This presentation addresses light therapy and theory, proven facts about light therapy uses, and practical tips for effectively setting up a light therapy device in your practice.
2:30-3:30pm
Mineral Makeup in Medical Practice (Live Demonstrations)
Marie Piantino, L.E.
President, Co-Owner, MS Skintechnical
Since the introduction of more aggressive Laser/IPL treatments the need to provide camouflage to the patient post care program has increased. This lecture will help you understand the ideology and the science behind mineral makeup and also show you the benefits and noticeable results your patients will see. Understand why mineral makeup is making its entrée into the medical aesthetic market and why you should incorporate it into your practice
3:30-3:45pm
Break
3:45-4:45pm
Skin Resurfacing - Microdermabrasion Equipment, Protocols and Techniques (Live Demonstrations)
Marie Piantino, L.E.
President, Co-Owner, MS Skintechnical
Skin resurfacing using Microdermabrasion has evolved since inception and this lecture will provide a non biased discussion of available Microdermabrasion equipment, protocols for use and techniques that aesthetic practitioners have found effective and useful.
4:45-6:00pm
TBD
Friday, November 9th
8:00am-8:10am
Opening Remarks
Joseph McWherter, M.D.
Chairman, Conference Planning Committee Age Management Medicine Group
Editor, e-Journal of Age Management Medicine
8:10-8:30am
Presentation of the Alan P. Mintz, M.D. Award for Excellence in Age Management Medicine and Address
8:30-9:30am
FEATURED SPEAKER
New and Emerging Treatment Strategies for Female Sexual Function Complaints
Jennifer R. Berman, M.D.
Director, Berman Women’s Wellness Center, Beverly Hills, CA
Dr. Berman, a recognized expert in the field of female urology and female sexual medicine, will discuss new and emerging treatments for female sexual complaints and dysfunction including Female Sexual Arousal Disorder (FSAD). This will include the importance of a complete physical examination and physiologic evaluation of the female sexual response to detect any abnormalities in the genital region and development of treatment strategies for sexual function complaints.
9:30-10:30am
Nutrients for the Skin and Optimal Aging
Derrick M. DeSilva, Jr., M. D.
Medical Teaching Faculty, John F. Kennedy Medical Center, Edison, NJ
Attending Physician / Co-Chair Department of Complimentary Medicine, Raritan Bay Medical Center
The skin is the largest organ in the human body. It is also the largest organ of elimination in the human body. It is, by far, one of the most used and abused organs. For many years we have only focused on “healing” the skin from the outside. True healing of this vital organ must focus on healing from the inside. The lecture will not only deal with the topical nutrients necessary for healthy skin, but will pay closer attention to the “healing nutrients” that must become part of our daily regiment for overall better health particularly as we age.
10:30-11:00am Break / Visit Exhibits
11:00am-12:00pm
Bio-Markers of Aging. Chronological vs. Physiological Markers....What to Measure and Follow up Procedures
Christopher G. Rao, M.D., F.A.A.F.P.
Staff Physician, Cenegenics Medical Institute, Boca Raton, FL
Evidence based research will be provided on objective measurements which clinicians can use in office to estimate physiological age as they effectively develop and monitor individualized patient treatment plans. This method allows for positive feedback to the patient and physician and may provide a reduction in the risks for disease as patients age.
12:00-1:15pm Lunch
1:15-2:15pm
Trust Your GUT Feelings; A Clinical Guide to Assessing and Treating Gastrointestinal Dysfunction; Dysbiosis, Irritable Bowel Syndrome, IBD
Erin Lommen, N.D.
CEO / Associate Medical Director, Labrix Clinical Services
Associate Medical Director, Center for Integrative Medicine
Digestive disorders have been cited as the second leading cause of absenteeism from the workplace after the common cold. Irritable bowel syndrome is estimated to account for up to 50% of all patient visits in gastroenterological ambulatory departments. In Naturopathic Medicine, it is now suggested that up to 70% of all chronic disease states initially are caused by problems with the digestive tract. What is a blanket term for a myriad of symptoms often falls under “Irritable Bowel Syndrome” but this can range from heartburn to reflux, to constipation and / or diarrhea, to systemic immune compromise and chronic disease. This presentation will outline a systematic and clinically relevant approach to diagnosing and treating your patient’s functional gastrointestinal disease.
2:15-3:15pm
The New Carbs vs. Protein Battle: Solving the Insulin-Serotonin Dilemma
Cheryle R. Hart, M.D.
Medical Director, Wellness Workshop, Spokane, WA
Board Certified, Obstetrics & Gynecology, Board Certified, Bariatrics
Over half of American adults are battling with at least one of the consequences of Insulin Resistance: hypertension, abnormal cholesterol, high triglycerides, obesity or glucose intolerance. Many have successfully controlled, even reversed, these complications by eating high protein, low carbohydrate diets. Unfortunately, we now realize that these specific diets deplete serotonin, especially in menopausal women. Lowered serotonin leads to mood disorders, depression, appetite control problems, yo-yo dieting and insomnia. In addition to presenting the research and mechanics behind this challenging insulin-serotonin dilemma, Dr. Hart will present successful dietary solutions that simultaneously regulate insulin while increasing serotonin.
_______________________________________________________________________
3:15-3:45pm Break / Visit Exhibits
3:45-4:45pm
Heavy Metals, the Impact on Premature Aging: Appropriate Evidence-Based Clinical Interventions
Rashid A. Buttar, D.O.
Visiting Scientist, North Carolina State University
Medical Director, Center for Advanced Medicine & Clinical Research
The role of oxidative stress in aging is now a well established and well documented clinical concern. However, the emphasis so far in clinical medicine has been on improving the anti-oxidant levels but not towards the reduction of substances that increase oxidative stress. This lecture will present the role of heavy metals in chronic diseases associated with aging, the resulting oxidative stress associated with heavy metals and the various clinical interventions that have been used to reduce this oxidative burden.
4:45-5:45pm
Chemical Sensitivities, Toxins, and Aging: How to Survive on a Toxic Planet
Stephen D. Nugent, N.M.D., Ph.D., P.D.D., M.A., C.N.C.
Executive Director, Complementary Health and Education, Mannatech.
President Emeritus, American Naturopathic Medical Association, (ANMA)
Concentration of toxins in our homes is 5 to 10 times greater than outdoors with 150 household chemicals that have been linked to allergies, birth defects, cancer, and physiological abnormalities. Since 1930 more than 75,000 additional synthetic chemicals have been introduced into our environment yet only a small fraction of these have been tested for safety. Many toxins are a perfect fit for hormone receptor sites. Xeno-estrogens have feminized certain species to the brink of extinction. Toxins induce oxidative stress and promote aging as well as numerous disease processes. Learn how to help your patients from the ravaging affect of daily toxins by elimination of toxins at the cellular level and reduction of future damage through nutrition.
________________________________________________________________________
5:45-7:00pm Attendee Cocktail Reception
Saturday, November 10th
8:00-9:00am
Effectiveness of Topically Applied Steroid Hormones and Effective Monitoring Methods
Jay H. Mead, M.D.
Fellow, American Society of Clinical Pathologists
President & Medical Director, Labrix Clinical Services
The presentation will focus on the pharmacokinetics of topically applied hormones and the current scientific support for bio-identical hormones as compared to the recent evidence of the harmful effects of the pharmaceutical analogs.
9:00-10:00am
Interpretation of the WHI Study and Reversal
Joseph McWherter, M.D.
Chairman, Conference Planning Committee Age Management Medicine Group
Editor, e-Journal of Age Management Medicine
In 2002, the Women’s Health Initiative (WHI) study stunned the medical community, reporting a series of very controversial results on the benefits and side effects of hormone replacement for women. Since that time research has continued and many press reports have indicated that many of the WHI study findings have been reversed. This lecture will examine the literature and review the research and findings that have taken place since 2002 providing an interpretation of the original study and subsequent findings.
10:00-10:30am Break / Visit Exhibits
10:30-11:00am
Why Do Centenarians Live So Long
L. Stephen Coles, M.D., Ph.D.
Director, Supercentenarian Research Foundation
Visiting Scholar, Department of Computer Science, UCLA
The Autopsy Report of a 106-year-old veteran of World War I, performed at the Palo Alto VA Hospital in July 2007, reveals a uniform rate of aging in all his organs that was slower than normal throughout his life. Indeed, superficially, his organ systems appeared to be those of an "80 year old" not a 106 year old. The preliminary diagnosis was that he died of "old age," i.e., there was no particular organ system conspicuous for primary cause of death. Several supercentenarian autopsies performed in the Pathology Department at UCLA have demonstrated Systemic TTR Amyloidosis of the heart as the primary cause of death. However, with H&E staining of the pituitary gland, for example, this subject did not demonstrate any aggregation of amyloid fibrils in his vessels. There was simply cellular decomposition and the presence of a few eosinophils.
11:00-12:00pm
A New Paradigm for Treating Age-Related Growth Hormone Insufficiency
Richard F. Walker, Ph.D., R.Ph.
Executive Director, Society for Applied Research in Aging (SARA)
Editor in Chief, Clinical Interventions in Aging
President, Regulatory and Scientific Consulting Services
Growth hormone replacement therapy (GHRT) using recombinant human growth hormone (rhGH) has been embraced by many age management practitioners as one of the most effective methods for opposing somatic senescence that is currently available. However, its routine use has been controversial because few clinical studies have been performed to determine the potential risks of long-term therapy. Also, certain medical and legal issues have not been resolved causing some practitioners to restrict their use of the product. One possibility that is receiving growing attention is the use of growth hormone releasing factor 1-29 NH2-acetate or sermorelin that recently became available to practitioners for use in longevity. Thus, the specific objectives of this presentation are to compare and contrast the qualities of rhGH and sermorelin for use in GHRT for opposing age-related GH insufficiency. Thereby, a new and perhaps more effective, safe and legal paradigm for this commonly used clinical intervention in aging may be identified.
12:00-1:15pm Lunch
1:15-1:45pm
The Effect of Multimodal Treatment Program in Migraine Management
Sergey A. Dzugan, M.D., Ph.D.
CEO, Fountain Institute, Deerfield Beach, FL
George W. Rozakis, M.D.
Private Practice Ophthalmology, North Olmsted, OH
Migraine affects about 10-15% of the populations in different countries. The goal of this presentation is to evaluate the effect of a multimodal treatment program and role of hormone restorative therapy in migraine management. Our results show that all patients responded to migraine management. We do not have any patients who still have migraine after they started to use this program. A new multimodal method of migraine treatment could be an effective physiologic intervention for migraines and could be an inexpensive resource for the healthcare system. Hormone restorative therapy is the core element of multimodal treatment program.
1:45-2:45pm
Results of the University of Miami / Cenegenics Retrospective Study in Age Management Medicine
Enrique Ginzburg, M.D.
Professor of Surgery, University of Miami School of Medicine
Nancy Klimas, M.D.
Professor of Medicine, University of Miller Miami School of Medicine and the Miami VA Medical Center
President, International Association for Chronic Fatigue Syndrome / ME
Discussed will be the latest research results of an effective program of hormone modulation for men & women, low glycemic nutrition, and exercise instruction on select outcomes indicative of disease risk and the subjective impression of
quality of life in a private practice.
2:45-3:15pm Break / Visit Exhibits
3:15-4:15pm
Clinical Use of hGH for Adult Growth Hormone Deficiency
Robert D. Willix, Jr., M.D., FACSM
CEO, Cenegenics Medical Institute of Boca Raton
Lecture will provide clinical protocols on the use of growth hormone for adult deficiency as an adjunct to Age Management Medicine, including guidelines for when and how to use growth hormone for true patient benefit. The presentation will include rational treatment targets for practicing physicians and criteria for administering human growth
hormone to adult patients. Course will discuss the rational use of the laboratory for adult growth hormone deficiency. Also presented will be diagnostic criteria and treatment outcomes, all based on the evidence in the medical literature.
4:15-5:15pm
Legal Aspects and Implications of Prescribing Hormones
William Stilling, R.Ph., J.D.
The use of hormones including growth hormone from a legal perspective. How clinicians should conform and work with FDA regulations and AMA guidelines.
5:15-5:45pm
Panel / Attendee Discussion of the Legal Aspects and Implications of Prescribing Hormones
Joseph McWherter, M.D. - Moderator
William Stilling, R.Ph., J.D.
Richard F. Walker, Ph.D, R.Ph.
Steven L. Russell, R.Ph.
Michale Barber, M.D.
Robert D. Willix, Jr., M.D.
Interactive session based upon preceding conference sessions involving the use of hormones by physicians in their practice and the subsequent legal provisions and implications. The panel consists of experts who practice Clinical Age Management Medicine, Pharmacists who compound and dispense hormone products and an Attorney / Pharmacist with experience in the legal aspects associated with Age Management Medicine and in dealing with FDA and AMA guidelines regarding the use of hormones. Attendees are encouraged to bring questions with them to this session and will be given the opportunity to present to the panel for discussion.
Sunday, November 11th
8:00-8:45am
Age Related Mild Bone Loss (Osteopenia): To Treat or Not to Treat?
Israel Yoles, M.D.
Coordinator, The Menopausal Clinic, The Center for Women’s Health, Ashdod, Israel
Attending Physician, Sheba Medical Center, Department of OBGYN, Ashdod, Israel
Osteoporosis and osteoporotic fractures have reached epidemic levels and its prevention presents a major challenge. There is no doubt that osteoporosis should be treated. However, normal bone does not turn all of a sudden to become osteoporotic. Due to aging processes, lack of estrogen, reduced activity and other factors, the bone starts to loose its content and strength. This stage, between normal bone and osteoporosis, is called osteopenia. There is an unsolved debate whether osteopenic women should be treated. On the one hand, osteopenia may lead to osteoporosis and fracture, so osteopenic woman should be treated. On the other hand, two out of three osteopenic women will never develop osteoporosis or fractures. The treatment is not harmless and the decision for preventive treatment of a very large population for many years has significant financial implications. The dilemma whom to treat with which agent, will be discussed.
8:45-10:15am
Andropause and the Aging Male
Michale J. Barber, M.D.
Chief Executive Officer, Cenegenics South Carolina
Paul Hueseman, Pharm. D.
President, Bellevue Pharmacy
Drs. Barber and Hueseman will explore origins, symptoms and diagnosis of Andropause in the Aging Male including testosterone deficiency, testosterone and the relationship to the heart, DHEA, Estradiol, Progesterone, and dietary supplements. Discussion will include initial patient clinical examination and observations, procedure for testing using saliva, urine and blood, diagnosis and development of a treatment plan, plus treatment options using hormone therapy and delivery agents such as capsules, sublingual tablets, patches, transdermal applications, injections and pellets and dosing guidelines.
10:15-10:45am Break / Visit Exhibits
10:45-11:15am
Mitochondrial Functional Analysis - A New Method for Assessing Age Management Medicine Strategies
Frank A. Shallenberger, M.D., H.M.D.
Medical Director, Nevada Center for Anti-Aging Medicine, Carson City, NV
Using respiratory gas exchange data, the following measurements can be determined: resting ATP production, resting ATP production from fat, maximal ATP production from fat, and maximal aerobic ATP production. When compared to standardized expected ranges, it is possible to measure mitochondrial efficiency in a medical practice setting. Since mitochondrial efficiency is the determining factor in the rate of aging and the risk of all cause mortality, this data can be used to insure that that the Age Management Medicine strategies being used in each individual patient are effectively optimizing mitochondrial function in that patient.
11:15-12:00pm
Report on Clinical Trials Involving Telomerase Activation and the Impact on Aging
Joseph M. Raffaele, M.D.
Co-Founder, PhysioAge Medical Group
Scientific Advisory Board, TA Sciences
Telomere Biology is the emerging field in Age Management Medicine. Futurists have predicted for decades that “IF” telomeres, the protective DNA located at the ends of all chromosomes, could be restored, a host of aging conditions could be postponed or reversed. Scientists have discovered a way to turn the hTert gene back on, allowing it to express telomerase and repair damaged telomeres. Clinical trials performed in vivo in humans in 2005 show statistically significant improvements in: Immune function, Male sexual function, Vision, Skin, Well-being and Energy.
12:00-1:00pm Lunch
1:00-1:30pm
Case Presentation Series Using Established Age Management Medicine Protocols
Jeffry S. Life, M.D., Ph.D.
Senior Physician, Cenegenics Medical Institute
As a prelude to the open panel and attendee case presentation discussion Dr. Life will provide attendees with several actual cases from his existing Age Management Medicine practice and discuss these cases from a clinical perspective highlighting necessary testing methods, interpretation of data, development of treatment plans and individualized treatment protocols.
1:30-3:00pm
Panel Discussion with Attendee Submitted Case Presentations – Best Practices in Age Management Medicine
Joseph McWherter, M.D. - Moderator
Derrick DeSilva, M.D.
Michale Barber, M.D.
Robert Willix, M.D.
Steven L. Russell, R.Ph.
Jeffry S. Life, M.D., Ph.D.
This session will feature short problematic case presentations with comment and interaction on best Age Management Medicine practices by our expert panel, audience interaction is also encouraged. In order to prepare for this session attendees are asked to submit by email no more than a one page case history for the panel to review and consider. Cases must have the name of the person making the submission, their contact information and should be emailed no later than October 15, 2007 to gfillmore@agemed.org Attendees with cases that are selected will be asked to stand and briefly (2-3 minutes) present their case to the audience for discussion.