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Agenda November 2017
When the NIH launched their Precision Medicine Initiative it brought the future of healthcare to the forefront of everyday clinical medicine. Because of this high-profile program, patients are going to demand that doctors acquire a better understanding of Precision Medicine— the term, the concept and clinical practice. Physicians who do not understand Precision Medicine or who have not yet begun to incorporate these concepts into their practice risk being left behind, as medicine begins a fundamental shift in the direction of a personalized approach empowering patients to a healthier life. Physicians attending this Track who are new to or have begun this shift will benefit from these insightful lectures and interaction with these experts as they expand their knowledge and refine their protocols.
7:00 AM - 7:45 AM
Compounds That You Can Use in Your Practice and Laws Governing Them
Presented by David J. Metayer
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by University Compounding Pharmacy
8:00 AM - 8:45 AM
Precision Medicine: Making Omics Data Actionable
Florence Comite, M.D.
CEO & Founder, Comite Center for Precision Medicine, New York, NY
Member, AMMG Conference Planning Committee
Lecture Description:
The future of medicine is here today! As health professionals and patients, we have been stuck for decades in a reactive, sick-centric model that prescribes “one size fits all” disease-care to the masses. Precision medicine flips this perspective 180 degrees. By integrating and interpreting longitudinal, n-of-1 data about an individual’s genomics, metabolomics and hormonal profiles, personal and family history, and lifestyle, precision medicine has the power to provide each individual with actionable and personalized interventions for optimal healthy longevity.
8:45 AM - 9:30 AM
Personalized Profiling of Diabetes Using Longitudinal Multi-omics Data
Hannes Röst, Ph.D.
Assistant Professor, Terrence Donnelly Centre for Cellular and Biomolecular Research; Department of Molecular Genetics; University of Toronto, ON, Canada
Lecture Description:
Obesity is a “general” health concern – a worldwide health epidemic and a major cause for cardiovascular disease and type 2 diabetes mellitus (T2DM) – that necessitates precise and personalized intervention. In fact, there is great heterogeneity among individuals of similar weight and BMI in terms of insulin sensitivity; and the underlying molecular factors driving disease progression are currently poorly understood. This lecture illustrates how a personalized omics approach to large-scale longitudinal data can offer a novel insight and new strategies for predicting and preventing disorders of aging, and specifically obesity-associated metabolic disease.
9:30 AM - 10:15 AM
A Precision Health Approach to IV Therapy
Kelly Bender, N.D.
CEO & Co-founder. Pure Vitality Rejuvenation Center, Los Angeles & Beverly Hills, CA
CEO & Founder, KB Healthy, Los Angeles, CA
Membership Chair, California Naturopathic Doctors Association
Lecture Description:
This lecture will review the uses and contraindications of nutrient IV therapy as well as discuss methods of assessment for individual patients. These include laboratory testing, patient history, clinical presentation, patient environment, and lifestyle. Dr. Bender will describe how to formulate for a patient so treatments are safe, synergistic and effective. At the end of the lecture you should be able to start implementing this therapy in your practice on Monday.
10:15 AM - 10:30 AM
Break
10:30 AM - 11:15 AM
Personal Omics Profiling: Predicting Disease Risk in the Precision Medicine Era
Shannon Rego, MS, CGC
Licensed Genetic Counselor, Snyder Lab, Dept. of Genetics, Stanford University
Lecture Description:
The lecture will be an overview of the ways in which omics profiling including whole genome sequencing can provide a better understanding of personal disease risks and influence treatment in not only families with known genetic disease, but in the general population.
11:15 AM - 12:00 PM
Beyond Biomarkers: Precision Medicine Labs for Optimal Longevity
Francisco Carreño, Ph.D.
Exercise Physiologist, Comite Center for Precision Medicine, New York, NY
Lecture Description:
Your blood doesn’t lie! Blood-based biomarkers collected regularly over time, and analyzed in the context of an individual’s total health can reveal vital patterns that inform precise and personalized intervention for optimal health. This lecture looks at key panels related to longevity including carbohydrate metabolism, kidney and liver function, advanced lipids, inflammation and bone markers, hormones, and genetic risk factors; and the power of precision medicine to integrate and interpret findings to provide actionable, n-of-1 guidance to each individual.
12:00 PM - 1:30 PM
Lunch Break
12:00 PM - 1:00 PM
TA-65 Rejuvenates the Aging Immune System: Preliminary Results of a 500 Subject Controlled Trial
Presented by Joseph M. Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
1:30 PM - 2:15 PM
Metabolomics and its Role in Precision Medicine
Adam Kennedy, Ph.D.
Director, Scientific Discovery and Application, Metabolon, Inc., Morrisville, NC
Lecture Description:
Environment, lifestyle and genetics exert influence on health by changing our metabolic composition. Metabolomics provides a snapshot of the current health status and creates actionable clinical information, making it a valuable first-line health assessment tool. We’ll discuss the technology, how it translates into the clinic today and its role in the future of medicine.
2:15 PM - 3:00 PM
Whole Exome Sequencing: An Actionable Precision Medicine Tool
Andrew Mills, Ph.D.
CEO and Founder, New Amsterdam Genomics, New York, NY
Lecture Description:
DNA sequencing has been the “next big thing” in the clinic for years. We argue there are three major developments that are finally making DNA sequencing very useful: 1) analyzing a much larger portion of the genome, 2) using computer technology to facilitate analysis, and 3) standardizing a framework for applying genetic findings. We provide data and evidence from our lab to demonstrate these key points.
2:30 PM - 7:00 PM
Exhibits Open
3:00 PM - 3:45 PM
Break / Visit Exhibits
3:45 PM - 4:30 PM
Telomere Technology: End of DNA As We Know It
Joseph M. Raffaele, M.D.
CEO, PhysioAge Systems, New York, NY
Co-Founder, PhysioAge Medical Group, New York, NY
Lecture Description:
The ends of DNA—telomeres—have been the subject of intense investigation over the past three decades. We now know that telomeric DNA is profoundly different from the rest of our genome. While there are no polymorphisms of the non-coding telomeric sequence of repeating TTAGGG nucleotides, the number of these repeats (telomere length) is highly heritable, highly variable, and highly malleable over the lifespan. Thus, telomere length is the only part of our DNA that is susceptible to modification by lifestyle, diet, exercise, supplements and drugs. It therefore offers an opportunity at the intersection of genetics and epigenetics to inform precision medicine. In this talk, I will discuss how to apply this emerging telomere science (and some new data) to everyday practice through case studies demonstrating how telomere length can be measured, interpreted, and improved.
4:30 PM - 5:30 PM
Panel Discussion: Driving Precision Medicine Into the Clinic: Promises & Challenges
Panel Chair: Florence Comite, M.D.
Panel: Hannes Röst, Ph.D., Kelly Bender, N.D., Shannon Rego, MS, CGC, Francisco Carreño, Ph.D., Adam Kennedy, Ph.D., Andrew Mills, Ph.D., Joseph M. Raffaele, M.D.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests.
Held in Conference Networking and Exhibits Center
Course is designed to familiarize physicians and healthcare professionals with the basics of hormones for men and women, and an introduction into the evidence based use of hormones to replace and optimize hormone levels within the context of clinical Age Management Medicine.
7:00 AM - 7:45 AM
Compounds That You Can Use in Your Practice and Laws Governing Them
Presented by David J. Metayer
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by University Compounding Pharmacy
8:00 AM - 9:00 AM
Quantum Interventional Endocrinology
John K. Crisler, D.O.
President, Founder & CMO, Superior Age Management, AllThingsMale Center for Men's Health, Lansing, MI
Dept. of Community & Family Medicine, Michigan State University College of Osteopathic Medicine, East Lansing, MI
Lecture Description:
A new perspective for best directing the care of our hormonal patients, loosely analogous to quantum physics, which describes reality by explaining the simultaneous existence of that which appear as mutually exclusive conditions. Lecture will describe and explain the limitations of both traditional Endocrinology and Epidemiology with respect to advancing the field of Interventional Endocrinology and build upon the works of the greatest minds in our field, such as Drs. Dach, Gordon, Mintz, Rouzier, Shippen and Pati to provide an incrementally more unified theory of actions within the hormonal matrix. That while a fundamental understanding of the workings of the body will always be foundational to the practice of medicine, getting the “feel” for actions within the hormonal matrix is necessary in a field where we have just begun to scratch the surface with respect to our understanding of same. At this point the top Thought Leaders agree achieving the best results sometimes seem more an art than a science, after dedicated and constant study, combined with years of acquired clinical experience. This always has been how clinicians evolve into true healers. Abundant application of some of the latest techniques in Interventional Endocrinology, in illustrating the above points, will provide the participant with practical clinical “pearls” they may immediately implement into their own practices. Case studies will be provided.
9:00 AM - 10:00 AM
Testosterone for Men
Rob Kominiarek, D.O., FACOFP
President and Medical Director, ReNue Health, Springboro, OH
Assistant Clinical Professor, Ohio University College of Osteopathic Medicine
Lecture Description:
This lecture will explore the basics of testosterone therapy for men, starting with initial laboratories and exploring the numerous treatment options available to the physician for resolution of symptoms associated with partial androgen deficiency. We will further explore how to deal with unanticipated, new, awful, frightening, and frustrating anxiety disorders, panic attacks and their often-disabling symptoms. What happened after you started therapy? This lecture will explain the mechanisms by which underlying, unexposed anxiety issues can be manifested after the addition of testosterone. Dealing with the increase of serotonin re-uptake transporter protein, decreasing magnesium levels, MOA snp’s and progesterone, DHEA and pregnenolone decline. Attendees will be able after this lecture to implement these strategies in their daily practice to immediately benefit their patients.
10:00 AM - 10:15 AM
Break
10:15 AM - 11:15 AM
Adrenal, Thyroid, Pregnanalone, DHEA
Rebecca R. Murray, APRN, FNP-BC, CDE
Endocrine Nurse Practitioner, Institute for Hormonal Balance, Orlando, FL
Medical Director, Ward-Murray HealthCare Consulting, Groton, CT
Scientific Advisory Board, Designs for Health
Lecture Description:
“Wired and tired” is a phrase that describes so many patients that are seen in our practices but have been told by previous providers that there is NOTHING wrong as they do not fulfill the diagnostic criteria for an ICD-10 code. This lecture will explore in depth both the very subtle signs and symptoms of adrenal fatigue and suboptimal thyroid function in addition to the differential diagnosing of overt endocrine disorders of the adrenal and thyroid glands. The steroidogenic pathways in relation to the production and contribution of pregnanalone and DHEA in “hormonal balancing” will also be discussed. Treatment options will be reviewed that include pharmacology, lifestyle changes, natural therapies and the importance of nutritional supplements.
11:15 AM - 12:00 PM
Progesterone
Rebecca R. Murray, APRN, FNP-BC, CDE
Endocrine Nurse Practitioner, Institute for Hormonal Balance, Orlando, FL
Medical Director, Ward-Murray HealthCare Consulting, Groton, CT
Scientific Advisory Board, Designs for Health
Lecture Description:
Although progesterone is often referred to as the “hormone of pregnancy” as the origin of the name comes from the importance in “pro-gestation,” this hormone goes far beyond its role in placental integrity and maintenance of a pregnancy to full term. Progesterone is also a crucial metabolite intermediate in the production of endogenous hormones, including the sex hormones, corticosteroids, and the important role in the brain as a neurosteroid. This lecture will explore the signs and symptoms of “estrogen dominance/progesterone deficiency,” when and how to measure levels, ß and the benefits of various delivery systems such as oral, sublingual, transdermal, and intravaginal.
12:00 PM - 1:30 PM
Lunch Break
12:00 PM - 1:00 PM
TA-65 Rejuvenates the Aging Immune System: Preliminary Results of a 500 Subject Controlled Trial
Presented by Joseph M. Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
1:30 PM - 2:15 PM
Laboratory Testing
John K. Crisler, D.O.
President, Founder & CMO, Superior Age Management, AllThingsMale Center for Men's Health, Lansing, MI
Dept. of Community & Family Medicine, Michigan State University College of Osteopathic Medicine, East Lansing, MI
Lecture Description:
While taking a thorough Medical History produces about 80% of clinical decision making, laboratory testing is unarguably a crucial factor in the diagnosis, treatment, and follow-up care of the Interventional Endocrinology patient. During the “Quantum Interventional Endocrinology” lecture, we explored the implicit inability of classical Epidemiology in describing the hormonal landscape. Now with a new perspective of the benefits, limitations, and even the pitfalls of the various forms of laboratory testing, how is the practicing physician able to obtain an accurate picture of their patients’ true hormonal status? The available laboratory matrixes include blood, urine and saliva. Here we—in an unbiased fashion--delve into the claims made by those who provide these forms of testing. We also must appreciate the evolution of our laboratory methodologies, i.e. abandonment of inferior immunoassay techniques for more accurate and reliable mass spectroscopy. And because physicians must “operate” in the real world, how do we strategize the logistics of objective information management: patient lifestyle, compliance, ability to pay, and medical insurance coverage? The attendee will leave this lecture with not only a thorough understanding of all, but ready to implement same as soon as they return to their office.
2:15 PM - 3:00 PM
Testosterone for Women
Anna Cabeca, D.O., FACOG, ABAARM
Medical Director, Vida Pura Health, Golden Isles Medical, Inc., St. Simons Island, GA
Lecture Description:
This lecture will enhance the practitioner’s understanding of using androgens in women, specifically testosterone and DHEA, and the benefits, risks and techniques for prescribing. It will allow practitioners to get a level of familiarity with understanding androgens in women, and give an awareness of prescribing options.
2:30 PM - 7:00 PM
Exhibits Open
3:00 PM - 3:40 PM
Break / Visit Exhibits
3:40 PM - 4:35 PM
Estrogen: The Good, the Bad, and the Ugly
G. DeAn Strobel, M.D., FACOG
Founder and President, G. DeAn Strobel, MD, PA, Sherman, TX
Founder and President, Allure Laser & Medical Spa, Sherman, TX
Teaching Faculty, Medical Advisory Board, and Mentor, BioTE Medical, Irving, TX
Lecture Description:
During the presentation, Dr. Strobel will present information to explain basic physiology of estrogen as well as the various ways in which estrogen is metabolized. The lecture will also explain estrogen’s effects on the various organs of the body as well as how choosing the form of delivery can impact overall health. This lecture is intended for the non-gynecologist and a beginner in hormone replacement therapy who would like to better understand estrogen.
4:35 PM - 5:30 PM
Clinical Pearls to Make Hormone Replacement More Effective and Safe
John Sherman, N.D.
Consulting Physician, Tahoma Clinic, Tukwila, WA
Guest Host, Green Medicine Radio Show, KVI-AM, Seattle, WA
Lecture Description:
The benefits and risks of bio-identical hormone replacement will be presented, along with ways to synergize their effects with nutrition and lifestyle support. The importance of respecting human cyclic biorhythms will be outlined, with various ways to balance hormones without using hormones. The advantages and disadvantages of different application sites will also be reviewed. Explanation and treatment of hyperexcretion syndrome will be presented. Laboratory screening techniques will also be discussed comparing saliva, blood, and urine, with advantages and disadvantages of each. Techniques discussed can make your BHRT practice more reliable and highly successful.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
In response to attendee requests for information on aesthetic protocols and treatments which are office based and can be done by non-board certified Age Management Clinicians either full time or as an adjunct to their existing practice, AMMG presents this track in conjunction with the American Academy of Microneedling. The decision not to accredit this track was made so that attendees could be provided with business tools as well as the science and medical information necessary to implement these procedures. The goal is not to make this track commercial but to give speakers in this niche area the leverage to openly discuss procedures and answer questions that could be severely restricted in an accredited environment.
7:00 AM - 7:45 AM
Compounds That You Can Use in Your Practice and Laws Governing Them
Presented by David J. Metayer
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by University Compounding Pharmacy
8:00 AM - 9:00 AM
Laser Compliance Made Simple
John Cumiskey, D.C., CLSO
Certified Laser Safety Officer and Instructor, Co-Owner, Integrated Laser Solutions, LLC, Phoenix, AZ
Lecture Description:
This course will address laser compliance as it relates to medical and cosmetic lasers. It will classify laser compliance into two parts—laser safety and laser science—and the correlation between the two. The elements of laser safety and laser science will be highlighted as they relate to the medical or cosmetic laser operator. Laser Safety Officer rules and regulations as mandated by the American National Standards Institute and the Occupational Safety and Health Administration will be discussed. Examples will be given regarding the subjects that are included in basic laser science including basic laser physics and tissue interaction, as an example. The misconceptions on the requirements for Laser Science and Laser Safety will be illuminated. Examples and suggestions of how simple it is to become laser safety compliant are given. And finally, a brief mach course in laser science and laser safety will be conducted to allow attendees to understand the need for laser compliance.
9:00 AM - 10:00 AM
PRP Used with Fillers
H. William Song, M.D.
Founder and CEO, Omni Aesthetics, Oakland, NJ
Lecture Description:
Platelet-rich plasma (PRP) has been used for over 10 years in the areas of orthopedics, oral surgery, & wound care. These same tissue healing strategies are now increasingly being used for the treatment of facial cosmetics and for the relief of sexual dysfunction. Dr. Song will discuss the use of PRP facial aesthetics as well as sexual function in men & women. Learn about the uses of PRP in combination services and get a preview of what’s coming.
10:00 AM - 10:15 AM
Break
10:15 AM - 11:15 AM
Human Adipose Derived Stem Cells (hADSCs) and Their Role in Healing and Skin Rejuvenation
Jordan R. Plews, Ph.D.
Chief Scientific Officer & Co-Founder, Xytogen Biotech
Lecture Description:
Human stem cells hold a lot of potential, but many of the advancements made in the last 10 years have not made it beyond the academic laboratory. This presentation reviews human stem cells, including pluripotent and mesenchymal stem cells, with specific emphasis on adipose derived stem cells (ADSCs) and their potential for healing and rejuvenating the skin. The proteins produced by mesenchymal stem cells, their role in the natural healing process of the skin, and the results from their topical application will also be discussed.
11:15 AM - 12:00 PM
Micro Dermabrasion plus Infusion – Lecture & Demonstration
Jennifer T. Haley, M.D., FAAD
Founder and President, Haley Dermatology & Skin Care Center, PC, Scottsdale, AZ
Board Certified Dermatologist, Linder Dermatology and Skin Cancer Center, Scottsdale, AZ
Lecture Description:
Learn about the simplicity of combining Mechanical Resurfacing with Infusion and Peels. Dr. Jennifer Haley will explain the science behind mechanical resurfacing and how to combine with the science of peeling: what works what doesn’t. Also, utilizing such infusions as stem cell conditioned media and other topical ingredients. Jennifer will discuss why combining mechanical resurfacing with the peels is beneficial and how to implement into your practice.
12:00 PM - 1:00 PM
TA-65 Rejuvenates the Aging Immune System: Preliminary Results of a 500 Subject Controlled Trial
Presented by Joseph M. Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
12:00 PM - 1:30 PM
Lunch Break
1:30 PM - 2:30 PM
Microneedling: Amplifying Results with Radiofrequency Energy - Lecture & Demonstration
H. William Song, M.D.
Founder and CEO, Omni Aesthetics, Oakland, NJ
Lecture Description:
Creating a controlled injury to activate the healing cascade is the basis behind most of the non-surgical skin treatments in aesthetic medicine. The microneedling procedure is a very popular way of utilizing this concept because of the relatively low cost and rapid recovery time. The down side is the need for multiple treatments and a long lag time between receiving the treatment and seeing results. Fractionated laser treatments are available for those seeking faster and more robust results. Unfortunately, the cost, risks and down time associated with a laser makes it a less attractive option for most clinicians. Combined microneedling / radiofrequency devices are now available to bridge the gap between these approaches. Dr. H. William Song will discuss the mechanism of action of microneedling and radiofrequency and explain how this combination can be a safe and very effective way to amplify the results for common conditions like skin laxity and acne scars.
2:30 PM - 3:15 PM
Light Emitting Diodes: Fact or Fiction
Bertica M. Rubio, M.D.
Medical Director, Antiaging Regenerative Medicine Clinic, Redlands, CA
Medical Advisor, Rejuvenate Image Restoration, Refine and AQ Skin Solutions
Lecture Description:
LED or Light Emitting Diodes were first used in a NASA program for healing. How do we choose the right equipment and what are the key factors to look for? What do we use it for and what are the protocols for each treatment? Does price reflect quality? What wavelengths are needed and how many photons per square centimeter? All these questions will be answered in this lecture, as LED is rapidly becoming a vital part of the aesthetic menu and is an inexpensive addition to the physician office based protocols.
2:30 PM - 7:00 PM
Exhibits Open
3:15 PM - 3:45 PM
Break / Visit Exhibits
3:45 PM - 4:45 PM
Microneedling with Hands-on Procedure - Lecture & Demonstration
Marie Piantino, L.E.
President, Aesthetic Education Group LLC
Founder, American Academy of Medical Microneedling
Candice Drake Hopkin, M.L.E.
Creator
Owner, Candice Drake Cosmetics
Lecture Description:
Microneedling, CIT (collagen induction therapy) or vertical needling is a method of using an automatic device to perforate the tissue on the face and/or body. Tiny “micro” needles are used to create microchannels in the tissue which start a controlled wound healing action. This healing action is a natural process the body goes through after injury. Microneedling creates hundreds of thousands of microchannels in the dermas which heal themselves over the next several weeks. These tiny perforations also aid in product absorption, therefore peptides, hyaluronic acids & PRP (Platelet Rich Plasma) is topically applied during the microneedling process. Microneedling is gaining popularity in the medical aesthetic field because it can treat a variety of skin indications, and it is a high profit, non-invasive procedure that can be delegated to a nurse, MA or aesthetician.
4:45 PM - 5:30 PM
New Appeal of Private Label Brands
Sheila Malmanis, L.E.
President, MS Skintechnical, Inc., Phoenix, AZ
Lecture Description:
This informative lecture will introduce the multiple facets as to why physicians and spas are moving towards branding themselves through their own product line. Learn how the growth of private label has surpassed most premium brands in the medical aesthetic products market. Making the right choice and knowing the right questions to ask when researching a manufacturer or compounding pharmacy, knowing the percentages of active ingredients required when making claims, and knowing where to look for sources to research packaging are key to marketing your brand to make it successful.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
This full day program, TBI – A Clinical Approach to Diagnosis and Treatment, will provide to the attendees overwhelming information culled from peer-reviewed articles on Traumatic Brain Injury as the causative factor for personality changes, cognitive impairment and mood disorders leading up to suicide. The attendees will be walked through the literature discussing the effects of primary trauma and the secondary effects of inflammation and oxidative stress on functionality.
In conjunction with the Warrior Angels Foundation, a 501(c)(3) non-profit organization
A portion of the proceeds from this course will be donated to the Warrior Angels Foundation as they work towards their goal of providing personalized assessment and treatment for U.S. Military service members and veterans who have sustained Traumatic Brain Injury (TBI) while in the line of duty.
7:00 AM - 7:45 AM
Compounds That You Can Use in Your Practice and Laws Governing Them
Presented by David J. Metayer
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by University Compounding Pharmacy
8:00 AM - 8:30 AM
An Introduction to Traumatic Brain Injury
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
A 30-minute overview of trauma, inflammation, and how it impacts the cognitive and emotional functionality of the brain.
8:30 AM - 9:30 AM
Neurology, Neuropathology and Neuroendocrinology in Traumatic Brain Injury
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
60-minute discussion based upon literature about the specific cellular and biochemical cascades that are initiated by neuro-trauma. Expanding discussion on the indolent and stealth progression of the initial injury (primary) and the years of damage produced by the secondary injury.
9:30 AM - 10:15 AM
The Laboratory of Traumatic Brain Injury
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The assessment of neurotrauma using trophic, neurosteroids, and neuroactive steroids as markers for hormonal deficiencies that are caused by both the primary and secondary injuries associated with neurotrauma (TBI). The literature supported view that the “standard reference” ranges and “normal” reference ranges are not relative to the patient. Interpretation of the lab results using the Median Theory of optimal levels.
10:15 AM - 10:30 AM
Break
10:30 AM - 11:30 AM
Traumatic Brain Injury and Neurobehavior
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The impact of neurosteroid deficiencies on both personality and mental abilities is clearly discussed in peer-reviewed articles. Those same articles provide support for mood and anxiety disorders developing from loss of the regulatory effects of many of the neurosteroids that are produced in the brain.
11:30 AM - 12:00 PM
Supplementation for Traumatic Brain Injury - Part I
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The major impact of trauma is the production of secondary injury precipitated by free radicals and oxidative stress. The use of specific anti-oxidants and the regeneration of the glutathione system in the brain can help to regain a neuro-permissive environment that can allow for cellular repair and regeneration.
12:00 PM - 1:30 PM
Lunch Break
12:00 PM - 1:00 PM
TA-65 Rejuvenates the Aging Immune System: Preliminary Results of a 500 Subject Controlled Trial
Presented by Joseph M. Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
1:30 PM - 2:30 PM
Supplementation for Traumatic Brain Injury - Part II
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
Continuation of the 5th lecture with specific application and treatment of traumatic brain injury. A number of cases will be discussed.
2:30 PM - 7:00 PM
Exhibits Open
2:30 PM - 3:30 PM
Case Studies - Part I
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
15 comprehensive cases will be dissected and presented with attendees’ participation as a means of consolidating the information that will be shared throughout the day.
3:30 PM - 4:10 PM
Break / Visit Exhibits
4:10 PM - 5:30 PM
Case Studies - Part II
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
Continuation of the cases with attendee participation and Q & A. The goal of these cases is to allow the audience an opportunity to work out with the lecturer the initial evaluation of the patient, laboratory testing, interpretation of the test results, and selection of an optimal treatment protocol.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
7:00 AM - 7:45 AM
Use Medical Weight Loss To Expand Your Age Management Practice
Presented by Kimball Lundahl, D.C.
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by Healthy Habits
8:00 AM - 8:05 AM
Opening Remarks
Derrick M. DeSilva, Jr., M.D.
Chairman, AMMG Conference Planning Committee
Senior Attending Staff, Dept. of Medicine, Raritan Bay Medical Center, Perth Amboy, NJ
Teaching Faculty, JFK Medical Center, Edison, NJ
8:05 AM - 8:30 AM
Presentation of the Alan P. Mintz, M.D. Award for Clinical Excellence in Age Management Medicine
8:30 AM - 9:25 AM
Hormone Replacement Therapy in Women - Do We Focus More on the Risk than the Benefits?
Gary Donovitz, M.D., FACOG, FRSM
Founder and CEO, BioTE Medical, Irving, TX
Founder and President, Institute for Hormonal Balance
Lecture Description:
After the W.H.I. results were published in 2002, Time magazine's cover story was "Hormone Replacement Therapy is riskier than was originally thought—what's a woman to do?" Over the past 15 years we continue to focus on the risk and not the benefits. The evidence is weighted to the contrary. The benefits will be the focus of this talk.
Please note: Because of scheduling delays with planned publication, the lecture “Consensus Panel Guidelines for the Use of Testosterone in Women” could not be presented at this time. This lecture may be considered a prelude to that report.
9:25 AM - 10:10 AM
Testosterone Therapy & Hormonal Balance in Women: An n-of-1 Approach
Florence Comite, M.D.
CEO & Founder, Comite Center for Precision Medicine, New York, NY
Member, AMMG Conference Planning Committee
Lecture Description:
It’s considered “macho,” it’s controversial, it’s the primary male sex hormone. It’s testosterone (T). And it’s vital to female health. There are many questions and concerns about T therapy in women. Abandoning the misconceptions and unfounded concerns about T and T therapy will empower physicians to provide each female client with evidence-based, personalized intervention for optimal hormone balance and total health. This lecture looks critically at the literature and uses case studies to explore the benefits of an n-of-1 approach to T therapy in the context of a comprehensive precision medicine program to optimize carbohydrate metabolism, body composition, and total health, in pre- through post-menopausal women.
10:10 AM - 10:50 AM
Break / Visit Exhibits
10:50 AM - 11:35 AM
Women’s Sexual Health
Anna Cabeca, D.O., FACOG, ABAARM
Medical Director, Vida Pura Health, Golden Isles Medical, Inc., St. Simons Island, GA
Lecture Description:
This lecture will address Hot Topics in Women’s Sexual Health, which include Brain Gut connection of course! Lecture will highlight hormonal physiology and the connection to behavior, vaginal androgen therapy for vaginal restoration, and the modern day woman’s predominant issue of stress and how it affects us.
11:35 AM - 12:15 PM
Your Hormones and Breast Cancer…Friend or Foe?
Gary Donovitz, M.D., FACOG, FRSM
Founder and CEO, BioTE Medical, Irving, TX
Founder and President, Institute for Hormonal Balance
Lecture Description:
Today I am excited to lecture to you on one of my favorite subjects: Hormones and Breast Cancer. We know all HRT is not the same. All Breast Cancers are not the same. It is unfortunate we use these terms as though they were all encompassing. Think about it: there are bio-identical and synthetic hormones delivered in many different routes; there are many breast cancers, some with hormone receptors, some without. Some breast cancers are invasive and some are localized. We have been handcuffed to always looking for statistical significance and lost our best friend, clinical significance. How can we feel our best and avoid breast cancer…is that even possible?
12:15 PM - 1:30 PM
Lunch Break / Visit Exhibits
12:15 PM - 1:15 PM
Sub-Cutaneous Hormone Pellet Therapy – Alternative Medicine or an Alternative to “Bad Medicine” and a “Fascinating” Way to Help Patients
Presented by Gary S. Donovitz, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by BioTE® Medical
1:30 PM - 2:15 PM
Comprehensive Clinical Age Management Evaluation for Women
Cesar M. Pellarano, M.D.
Preventive Cardiologist, Miami, FL
President, Founding Partner and Chief Medical Officer, Hillstar Health LLC, Miami, FL
Lecture Description:
The age management evaluation and treatment of women is markedly different from the management of men. Where in men, we are constantly evaluating numbers and laboratory levels, the management of women is all about balance. In my opinion, the hormone management of women is 95% art. In this lecture I will point out the difference in managing women in regards to their age, menopausal status, symptomatology and their individual needs for hormone optimization. We will discuss the management of estrogen, testosterone, progesterone and thyroid in each of these groups. Also, how to evaluate each of these groups prior to treatment. After this discussion, the physician should have a good clinical grasp on how to approach, evaluate and treat the women in their Age Management Practice.
2:15 PM - 3:00 PM
Appropriate Prescribing of Hormone Replacement Therapy in Women with CAD or at Risk for CAD
George C. Shapiro, M.D., FACC
Adjunct Assistant Professor Clinical Medicine, New York Medical College, Valhalla, NY
Founding Partner, Cenegenics, New York City
Member, AMMG Conference Planning Committee
Lecture Description:
Hormone Replacement therapy (HRT) in women has had its ups and downs over the past 35 years. Observational studies in the 1980s and 1990s have shown a reduction in cardiovascular disease (CAD) in postmenopausal women using HRT. The Women’s Health Initiative (WHI) study in 1991 showed an increased risk of CAD while the estrogen only arm of that trial in 2002 showed no effect on CAD. The North American Menopause Society and the international menopause societies all do not recommend use of HRT to decrease CAD. The Kronos Early Estrogen Prevention Study (KEEPS) trial in 2012 from Harvard Medical School showed favorable effects of HRT in newly menopausal women. Other studies performed at the Mayo Clinic showed that HRT might have a role in preventing CAD. The current lecture will review some of the more recent published studies from peer reviewed medical journals. Topics will focus on how HRT is associated with a marked improvement in survival in postmenopausal women with advanced HF; how HRT significantly increases apolipoprotein A-I levels and decreases Lp(a) and the effects on serum markers of inflammation in women with CAD; and how HRT protects against smoking-induced changes in vascular structure and function. Results of a recent study presented at this year’s American College of Cardiology's 66th Annual Scientific Sessions that showed lower atherosclerosis and very clear survival benefits in women using hormone replacement therapy will also be discussed. New Biomarkers to
evaluate vulnerable plaques in women to see if they are candidates for HRT will also be addressed.
3:00 PM - 3:30 PM
Break / Visit Exhibits
3:30 PM - 4:45 PM
Laser Vaginal Rejuvenation
Johnny J. Peet, M.D.
Owner and President, Woodlands Medical Aesthetics Institute, The Woodlands, TX
Lecture Description:
Laser Vaginal Treatments: What is out there? How do I tell them apart? What is on the horizon? Hybrid fractional laser technology review: past and current research initiatives.
4:45 PM - 5:30 PM
Abnormal Uterine Bleeding
G. DeAn Strobel, M.D., FACOG
Founder and President, G. DeAn Strobel, MD, PA, Sherman, TX
Founder and President, Allure Laser & Medical Spa, Sherman, TX
Teaching Faculty, Medical Advisory Board, and Mentor, BioTE Medical, Irving, TX
Lecture Description:
During the presentation, Dr. Strobel will present evidence-based ways to evaluate and treat abnormal uterine bleeding seen in the perimenopause and menopause patients. This lecture is intended for the non-gynecologist who would like to better care for their female patients in the setting of abnormal bleeding.
5:30 PM - 7:00 PM
Reception Introducing AMMG’s Training and Certification in Age Management Medicine
Presentation by Kenneth Janson, M.D.
Open to all conference attendees
7:00 AM - 7:45 AM
The Spectacular Role of the Human Microbiome in Preventing Metabolic Endotoxemia, the Number One Cause of Mortality Worldwide
Presented by Kiran Krishnan, Microbiologist
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by Microbiome Labs
8:00 AM - 8:45 AM
The Three Year Veterans Traumatic Brain Injury Study
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
Starting in 2014, the Warrior Angels Foundation joined with the Millennium-TBI Centers to offer retired Special Operational Forces an alternative approach to their current treatment for Post-Traumatic Stress Disorder. Many were on a polypharmacy that created another form of disability associated with further cognitive and emotional turpitude. We started enrolling Veterans, on a first come basis, into the TBI project where each was drawn for neurosteroid and neuroactive steroid assessment along with a few markers of inflammatory risk (DHEA-s, Vitamin D3, Pregnenolone, Androgens and Estrogens), SMAC24, and CBC. Based upon their results we used the median of the range for each marker to direct treatment. An average of 6 nutraceuticals were used along with Clomiphene citrate and/or natural thyroid replacement when indicated. Enrollees were given the Millennium Program Questionnaire (MPQ) every 30 days as a subjective on treatment and monitoring laboratory testing every 3 months. This presentation will review the literature supporting our approach to TBI/PTS and then present the results of this 3-year study, 2014–2016, on 58 medically disabled veterans who now have their lives back and are off 90% of their medications.
8:45 AM - 9:30 AM
CBD in the Clinical Age Management Setting
Derrick M. DeSilva, Jr., M.D.
Chairman, AMMG Conference Planning Committee
Senior Attending Staff, Dept. of Medicine, Raritan Bay Medical Center, Perth Amboy, NJ
Teaching Faculty, JFK Medical Center, Edison, NJ
Lecture Description:
CBD (Cannabidiol) is emerging as a powerful supplement with a significant effect on our body’s endocannabinoid system. The endocannabinoid system has been shown to have a strong effect on the inflammatory, immune, cognitive and motor systems of the body. Cannabidiol (CBD) is one of over 80 cannabinoids, natural compounds found in industrial hemp. CBD and delta-9-tetrahydrocannabinol (THC) are the two main active compounds found in the cannabis plant and are therefore the most recognized and studied. Unlike THC, CBD does not produce psychoactive effects, and it seems to have natural protection against the marijuana high. CBD without THC has shown promising results in independent research and studies as a treatment for a variety of conditions ranging from: Antiemetic,Anticonvulsant Antipsyotropic Anti-inflammator Anti-oxidant Anti-tumoral Anti-anxiolitic/anti-depressant and more. We will review the basic science of CBD and the scientific evidence supporting the many applications of CBD.
9:30 AM - 10:15 AM
Donating Blood for Optimum Health and Longevity: Treatment of the Most Common Side Effect of Androgen Therapy with Precision Medicine
John Sherman, N.D.
Consulting Physician, Tahoma Clinic, Tukwila, WA
Guest Host, Green Medicine Radio Show, KVI-AM, Seattle, WA
Lecture Description:
The many benefits of donating blood on longevity, cancer, cardiovascular disease, diabetes and hospitalizations will be presented. A history of blood donating will be outlined, going back to early Egyptian and Greek practices, 3000 years ago, up to present day therapeutic phlebotomy, as a practice for longevity and healthy quality of life. Contraindications of blood donating will be presented, along with the theoretical reasons why it is so beneficial. The difference between erythrocytosis and polycythemia will be discussed. Donating blood could be the most underestimated therapy to prevent many 21st century diseases.
10:15 AM - 10:45 AM
Break / Visit Exhibits
10:45 AM - 11:30 AM
3 Peptides for a Wellness Practice
Edwin N. Lee, M.D., FACE
Assistant Professor of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL
Founder, Institute for Hormonal Balance
Member, AMMG Conference Planning Committee
Lecture Description:
There are about 300 theories of aging ranging from the neuroendocrine, free radical, cell membrane, Hayflick limit, mitochondria, cross link, autoimmune, glycation, and others. Most scientists have narrowed the specifics of what affects how we age down to 2 theories. The first group states that aging is natural and programmed into the body, while the second group of aging theories says that aging is a result of damage which is accumulated over time. Working on hormonal optimization, removing toxins, improving on nutrition, reducing stress, and increasing physical activity helps in slowing the aging process. In addition, using 3 peptides can also help in slowing the aging process. The peptides Epithalon, Thymosin Alpha 1 and BPC-157 help improve the telomeres, reduce inflammation, improve on the production of type 1 collagen and also improve the immune system. Pertinent medical studies on the 3 peptides will be reviewed in this talk.
11:30 AM - 12:15 PM
Progressive Peptide Therapy: A New Therapeutic Paradigm
Kathy O'Neil-Smith, M.D., FAARM
Private Internal, Integrative and Regenerative Medicine Practice, Newton, MA
Lecture Description:
Peptides are natural bio-regulators with diverse effects in the body and are emerging as a novel therapy for bio-regulation. Peptides function in cell-signaling and exert regulatory actions on neuro-endo-immune function. Presently, peptides are used in orthopedics, and neuro-endo-immune conditions for the treatment of injury, pain syndromes, IBD, brain health and immune system dysregulation.
12:15 PM - 1:30 PM
Lunch Break / Visit Exhibits
Complimentary Attendee Lunch Courtesy of AMMG Exhibitors
Served in the Exhibit Hall
1:30 PM - 2:45 PM
The Genomics of the Microbiome, an Emerging Science on the Environment’s Influence on Human Health and Disease
Zach Bush, M.D.
Founder & Medical Director, M Clinic
CEO, Seraphin Group, Inc., Charlottesville, VA
Lecture Description:
The beginning of health is increasingly understood to involve the myriad of relationships between the Gut-Brain systems. The emerging field of microRNA has revealed extraordinary involvement of the bacteria, fungi, and even the food we eat in regulating our human genome. Here we look at the environmental threats and the microbiome defense systems for resilient barriers to protect the immunologic systems of the immune systems of the peripheral and central nervous system, and point to practical methods for you and your patients to preserve genomic health through reconnection with our environment.
2:45 PM - 3:15 PM
Break / Visit Exhibits (exhibits close 3:30 pm)
3:15 PM - 4:00 PM
Translational Enteroimmunology: How Intestinal Inflammation & Enteric Dysbiosis Promote Endocrinopathy & Metabolic Syndrome
Discussion of Pathophysiology, Diagnostics & Therapeutics en route to sustained healing of chronic illness
Dushyant Viswanathan, M.D., ABIM, ABoIM, AACE
Medical Director, The Columbia Center for Integrative Medicine, Columbia, MD and Woodland Hills, CA
Lecture Description:
Enteric microbial dysbiosis leading to immune system activation and dysregulation, promote excess adrenal secretion of cortisol, shunting of steroidogenic precursors away from the generation of homeostatically essential anabolic hormones, as measured by decreases in salivary testosterone, progesterone, DHEA, and serum 25OH Vitamin D. Depletion of these hormones and relative excess and dysregulation of estrogens, in the setting of chronic inflammation facilitated by IL-1 and other inflammatory cytokines, and activation of innate lymphoid cells induced by gut dysbiosis, promote metabolic syndrome, increased tendency towards autoimmune pathology, weight gain, prothrombotic states, vascular inflammation, insomnia, chronic fatigue, impaired cognitive function (commonly memory impairment or cognitive fog), inflammatory dermatopathies & arthropathies, gonadal dysfunction, and cyclic menstrual abnormalities. This presentation intends to articulate pathophysiology, in light of currently understood mechanisms linking gut metabolomics with endocrine considerations. Clinically relevant diagnostic and therapeutic considerations will be articulated in the context of specifically illustrative case reports, with the conclusion that the cases mentioned are more the rule than the exception to the rule.
4:00 PM - 4:45 PM
Testosterone Optimization vs Statins
Cesar M. Pellarano, M.D.
Preventive Cardiologist, Miami, FL
President, Founding Partner and Chief Medical Officer, Hillstar Health LLC, Miami, FL
Lecture Description:
Testosterone optimization, along with nutrition and exercise has been shown to lower body fat and increase muscle mass. The amount of body fat we carry, in most individuals, is directly proportional to the amount of medications we take. In my practice, 100% of my patients require less medication for hypertension, diabetes and dislipidemia. I will show how testosterone optimization alters our HDL map, lowers our LDL while increasing our HDL. This, in turn, leads to a reduction in statin use. This is true in both men and women.
4:45 PM - 5:30 PM
Telemedicine: Where We've Come From, Where We Are, and Where We're Going
John J. Rush, M.D., FACEP, MBA, MHA
Age Management Physician, Washington, D.C.
Founder & Chairman, Longevity Physicians Insurance Company
Lecture Description:
Dr. Rush will discuss the history of Telemedicine and its integration into today's medical practice. The lecture will also provide insights into the changing attitudes and acceptance of Telemedicine by consumers and regulators. Finally, telehealth legal and regulatory concerns will be discussed including: Cross-State Licensure, Medical Malpractice and Liability, and Drug Prescribing. The attendee will gain a better understanding into how to better integrate telemedicine into their AMM practice.
7:00 AM - 7:45 AM
Liability Insurance for Age Management Medicine Physicians: Risk, Expenses, Coverage and the Potential of Savings
Presented by John Rush, M.D.
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by Longevity Physicians Insurance
8:00 AM - 9:00 AM
The Impact of Hormones, Toxins and the Microbiota on Mood
Filomena F. Trindade, M.D., MPH
Private Practice, Capitola, CA
Professor, Fellowship in Metabolic & Nutritional Medicine, Morsani School of Medicine, University of South Florida
Faculty, Hormone Module, Institute for Functional Medicine, Gig Harbor, WA
Lecture Description:
Mood disorders are an exceedingly common problem in our society today. Given our high stress and constantly changing world, mood disorders can present in many ways and be called by many different labels. Using functional medicine tools, the root causes of mood disorders can be identified and successfully treated. We will review the common presenting complaints, physical-exam findings, and the appropriate laboratory work-up. We will examine the proper treatment of mood disorders as they relate to hormone disruptions, the ability to detoxify, and the importance of a healthy gut microbiome. Specific attention will be given to the critical analysis and prioritization of laboratory testing needed to acquire objective data on these contributing factors. A critical analysis of the literature will provide a detailed look at the link between adrenal dysfunction, fatigue, and mood disorders, plus the association of depression with the gut microbiome. In addition, we will learn to utilize diet, lifestyle modification, nutrients, adaptogens, and hormone replacement to restore balance to the hypothalamic, pituitary, adrenal, gonadal, and gut axis.
9:00 AM - 10:00 AM
Role of Intermittent Fasting and Optimal Aging
Evelyn E. Cintrón Pagan, M.D.
President and Founder, Belladona Medical Wellness, Bayamón and Vega Baja, PR
Lecture Description:
Intermittent fasting (IF) is a term for an eating pattern that cycles between periods of fasting and eating. It is not related to which foods you should eat, but rather the timing of when you should eat. In the strict sense it is NOT a diet but rather a “pattern of eating.” Common intermittent fasting methods involve daily 16 hour fasts, or fasting for 24 hours, twice per week. Fasting is one of the oldest forms of “eating” in the world, and modern science has proven that it has many health benefits. Humans have actually been fasting throughout our evolution. At times it was done because food was just not available. It has also been a part of major religions, including Christianity, Buddhism and many others. These religions believe that fasting was very beneficial not only for the spirit but also for healing the body. Our ancestors didn’t have the availability of food all year-round. There were times when they couldn’t find anything to eat, and their bodies evolved and functioned without food for extended periods of time. Fasting from time to time is a more “natural” phenomenon than consuming many meals per day. There are some changes that occur in your body when you fast. The effects on Human Growth Hormone (HGH), Insulin and Leptin sensitivity, Ghrelin normalization, cellular repair, gene expression, biomarkers for inflammation and healthy metabolism, longevity and more will be looked at and studies to support these effects on the human body will be presented and discussed.
Clinical cases studies will also be presented, showing how Intermittent Fasting helps in Weight Management, Hormonal balance and Metabolic diseases. In the 21st century, it’s all about metabolic diseases. Many diseases are “dietary diseases.” The problem is that we are trying to use drugs to treat dietary diseases. We as age management physicians now have another tool called Intermittent Fasting to offer our patients with a multitude of health benefits.
10:00 AM - 10:30 AM
Break
10:30 AM - 11:30 AM
Quantifying Endothelial Damage to Predict Acute Coronary Syndromes: Identifying the Vulnerable Patient Through Inflammatory and Signaling Biomarkers
Doug Harrington, M.D.
Clinical Professor of Pathology, USC Keck School of Medicine, Los Angeles, CA
CEO & Lab Director, Global Discovery Biosciences, Irvine, CA
Lecture Description:
Blood lipids are normal in 50% of individuals suffering an acute coronary syndrome (ACS). Recent research has demonstrated that biomarkers can contribute to determining the “Vulnerable Patient.” Scientific data and case studies will illustrate the clinical utility of these modalities.
11:30 AM - 12:30 PM
The Redefining of Menopause as a Condition of Inflammation and Oxidation; It’s Not the Hormone but Its Home
Cheryl Burdette, N.D.
Education Director and Owner, Dunwoody Labs, Dunwoody, GA
Director of Education and Naturopathic Residency Program, Progressive Medical, Atlanta, GA
Faculty, Integrative Medicine Program, George Washington University, Washington, D.C.
Lecture Description:
It is well understood that hormones interact with the DNA in our body to influence metabolic and enzymatic control. Estrogen, for example, increases activity of glutathione peroxidase and decreases inflammatory activity of NFKappaB. As we age, estrogen declines and therefore its favorable influence on these end targets is altered. By managing the decrease in glutathione created when this occurs and the increase in inflammation, we have many other natural interventions that can be used that are less invasive than hormone therapy. By understanding not only hormone testing, but being able to evaluate the environment that hormones are in, we can monitor the physiologic significance of change in estrogen. Not only do these measurements increase clinical understanding, but they widen treatment options for addressing menopausal concerns. Functional medicine is a necessary cornerstone in safe and effective hormonal management and treatment.
12:30 PM - 1:30 PM
The Root Cause of Thyroid Disease
William Clearfield, D.O., FAAMA, DABMA, FAARFM
Medical Director, Clearfield Family Medicine & Ageless Zone Medical Spa, Reno, NV
Lecture Description:
An estimated 12 percent of the U.S. population develops a thyroid condition during their lifetime. 60 percent of those patients are symptomatic but unaware of their condition. Of the newly diagnosed and undiagnosed, fully 90% of them are due to the thyroid attacking itself, i.e. autoimmune maladies. I have lived in Reno, Nevada for approximately three years. I wrote an overview article on hypothyroidism in Healthy Beginnings Magazine in July of 2015 and the response (typically, “Dr. Clearfield, it was if we were in the same room and you were talking to and about me personally) was overwhelming. (http://hbmag.com/patientmysteriesareyouthyroiddeficient/). Autoimmune thyroid disease, specifically Hashimoto’s Thyroiditis is practically an epidemic in Northern Nevada. In my adopted hometown, it is poorly understood, poorly diagnosed and poorly treated. Patients, especially women, frequently present with anxiety disorders, depression, and dysthymic disease. The local “standard of care” is to run a TSH and if it is “normal,” treat the patient with antianxiety agents and antidepressants. Much to the chagrin of the local endocrinologists—one even wrote in a medical chart that I was a “shaman and a disgrace to my degree”—I am considered the thyroid expert in Reno, Nevada.
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