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Agenda April 2017
1:00 PM - 4:00 PM
Precision Medicine & Genomics Seminar (Non CME)
Florence Comite, M.D.
CEO & Founder, Comite Center for Precision Medicine, New York, NY
Member, AMMG Conference Planning Committee
Lecture Description:
This interactive three-hour seminar is designed to help physicians and health professionals understand the power and practicalities of integrating genetic testing in the clinic, and in the context of precision medicine. Case studies and reviews of genetic findings for those who underwent whole-genome sequencing at AMMG Las Vegas will be discussed. An opportunity to participate in advanced metabolic testing and whole-genome sequencing for future analysis will be shared as an exclusive offering for attendees of this event.
There is no charge for this course, but seating is limited - participants must contact us in advance to reserve their seat. Priority will be given to individuals who participated at the whole-genome sequencing blood draw at AMMG Las Vegas in November 2016.
6:30 PM - 8:30 PM
CERTIFICATION PROGRAM SPECIAL EVENT:
Strategies for Success in Navigating AMMG Certification Module 1 - Overview & Exam Prep Session (Non CME)
Mary L. Corry, RN, BSN
Medical Education Specialist, Worldlink Medical
Member, AMMG Certification Committee
Member, AMMG Conference Planning Committee
Lecture Description:
Exclusively for AMMG Certification Program participants. There is no charge for this course but you must contact us in advance to reserve your seat. This interactive two-hour course is designed to help participants prepare for the Module 1 Examination. Study materials will be covered and challenging areas will be identified as participants will learn necessary resources to help navigate them successfully.
• Introduction, Learning Styles, Resources and Test Revisions
• Vitamin D, Pathophysiology, Research articles for objectives
• Video from Dr. Holick.
• SHBG, Review Life Extension Article and its role with Estrogen.
• Cortisol, Pathophysiology, Link to DHEA, Objectives and link with Meditation.
• DHEA, Neuro-steroid, Objectives, dosages, when to take it.
• Pregnenolone, Objectives and Life Extension article.
• Vo2 Max, American Heart Association and American College of Sports Medicine updates.
• Quizlet Resources.
• Navigating the Test.
This course is designed to familiarize physicians and healthcare professionals with the basics of IV Nutrient Therapy. Covers evidence basis, basic pharmacology of selected IV nutrients, common clinical uses of IV nutrients and clinical case examples. While limited in scope due to time available, the purpose of the instruction is to provide an overview of the topic with an eye to safety and efficacy of this modality in practice.
(Training certificate available upon course completion)
7:00 AM - 7:45 AM
Forget What You Know About Probiotics!
Presented by Kiran Krishnan
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by MegaSpore Biotic
8:00 AM - 8:45 AM
History, Indications and Scientific Evidence-Based Rationale for the Clinical Use of IV Nutrient Therapy
Edwin N. Lee, M.D., FACE
Assistant Professor of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL
Founder, Institute for Hormonal Balance
Member, AMMG Conference Planning Committee
Lecture Description:
It is estimated that the human body consists of somewhere between 100-200 trillion cells conducting an excess of 500 billion chemical reactions each second. Our cells form the basic building blocks of life. For our cells to function properly one of the most basic ingredients that our cells need is nutrition. IV nutrition is the most effective way for our cells to receive nutrients. In addition IV nutrition is a powerful tool for regenerative medicine that can repair the body at a cellular level. Modern IV therapy has been around for about 50 years although the first IV infusion has been dated from 1665. A short history of IV nutrition, the science and indications for IV nutrition will be reviewed.
8:45 AM - 9:45 AM
Assessing the Patient & Development of an Individualized Patient Treatment Plan: Proper Lab Tests, Understanding Lab Results, Developing an Appropriate Clinical Course of Action
Paul S. Anderson, N.M.D.
Consulting Physician & Medical Director
CEO, Anderson Medical Group, Seattle, WA
Research Professor, Bastyr Integrative Oncology Research Center
Full Professor, Adjunct Faculty, School of Naturopathic Medicine, Bastyr University
Dan Carter, N.D.
Medical Consultant, Dr. Carter Consults
Partner, International IV Nutritional Therapy for Professionals
Nutrition Instructor, Sage School of Massage
Lecture Description:
In this session Drs. Anderson and Carter will present evidence-based information regarding the initial assessment and proper prescription of IV nutrient therapy for patients. The compilation of a therapeutic direction and treatment plan including patient history, relevant physical exam and laboratory studies will be discussed. Cautions and contraindications will also be integrated in this overview.
9:45 AM - 10:30 AM
Components of IV Nutrition and Equipment & Set Up Procedures: IV Bottles, Bags & IV Sets, Current FDA Rules for In-Office Compounding
Paul S. Anderson, N.M.D.
Consulting Physician & Medical Director
CEO, Anderson Medical Group, Seattle, WA
Research Professor, Bastyr Integrative Oncology Research Center
Full Professor, Adjunct Faculty, School of Naturopathic Medicine, Bastyr University
Dan Carter, N.D.
Medical Consultant, Dr. Carter Consults
Partner, International IV Nutritional Therapy for Professionals
Nutrition Instructor, Sage School of Massage
Lecture Description:
In this session Drs. Anderson and Carter will present evidence-based information regarding the current “best practices” of IV nutrient pharmacologic handling. Issues related to clean and sterile technique, sterile product handling and latest USP guidelines will be discussed.
10:30 AM - 10:45 AM
Break
10:45 AM - 12:00 PM
Considerations of IV Nutrition: Vitamins, Electrolytes, Trace Minerals, Amino Acids & Antioxidants
Paul S. Anderson, N.M.D.
Consulting Physician & Medical Director
CEO, Anderson Medical Group, Seattle, WA
Research Professor, Bastyr Integrative Oncology Research Center
Full Professor, Adjunct Faculty, School of Naturopathic Medicine, Bastyr University
Dan Carter, N.D.
Medical Consultant, Dr. Carter Consults
Partner, International IV Nutritional Therapy for Professionals
Nutrition Instructor, Sage School of Massage
Lecture Description:
In this session Drs. Anderson and Carter will present evidence-based information regarding the pharmacology, solution kinetics and administration of the basic units of IV nutrients in common practice. Safe dosing and combinations of agents will be discussed.
12:00 PM - 1:00 PM
Telomere Biology Today
Presented by Joseph Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
12:00 PM - 1:30 PM
Lunch Break
1:30 PM - 2:45 PM
Properly Calculating Osmolarity and Potential Side Effects/Problems During and After IVs—How to Identify and Treat Them
Kathryn Retzler, N.D.
HormoneSynergy Clinic, Portland, OR
Lecture Description:
This lecture will offer a step-by-step guide in osmolarity calculation of IV formulas. Participants will also receive guidance on how to identify and manage possible complications and emergencies.
2:30 PM - 7:30 PM
Exhibits Open
2:45 PM - 3:30 PM
Break / Visit Exhibits
3:30 PM - 4:15 PM
Complications of IV Nutrition and / or Nutrient Deficiency
Paul S. Anderson, N.M.D.
Consulting Physician & Medical Director
CEO, Anderson Medical Group, Seattle, WA
Research Professor, Bastyr Integrative Oncology Research Center
Full Professor, Adjunct Faculty, School of Naturopathic Medicine, Bastyr University
Dan Carter, N.D.
Medical Consultant, Dr. Carter Consults
Partner, International IV Nutritional Therapy for Professionals
Nutrition Instructor, Sage School of Massage
Lecture Description:
In this session Drs. Anderson and Carter will present evidence-based information regarding the potential complications encountered in IV nutrient therapy. They will use their combined decades of experience managing IV infusions and complications to present strategies for prevention of complications as well as intervention should those complications occur.
4:15 PM - 5:00 PM
Common IV Nutrition Protocols: Vitamin and Mineral Formulas, Custom Hydration Formulas, Low and High Dose IV Vitamin C, Glutathione, Lipoic Complexes, Phosphatidyl Choline
Paul S. Anderson, N.M.D.
Consulting Physician & Medical Director
CEO, Anderson Medical Group, Seattle, WA
Research Professor, Bastyr Integrative Oncology Research Center
Full Professor, Adjunct Faculty, School of Naturopathic Medicine, Bastyr University
Dan Carter, N.D.
Medical Consultant, Dr. Carter Consults
Partner, International IV Nutritional Therapy for Professionals
Nutrition Instructor, Sage School of Massage
Lecture Description:
In this session Drs. Anderson and Carter will present evidence-based information regarding more specific and advanced IV nutrient therapies. These therapies are often considered “add on” or adjunctive therapies to the basic nutrients. They often carry specific pharmacologic and safety parameters which will be discussed.
5:00 PM - 5:30 PM
Case Studies
Paul S. Anderson, N.M.D.
Consulting Physician & Medical Director
CEO, Anderson Medical Group, Seattle, WA
Research Professor, Bastyr Integrative Oncology Research Center
Full Professor, Adjunct Faculty, School of Naturopathic Medicine, Bastyr University
Dan Carter, N.D.
Medical Consultant, Dr. Carter Consults
Partner, International IV Nutritional Therapy for Professionals
Nutrition Instructor, Sage School of Massage
Lecture Description:
In this session Drs. Anderson and Carter will present evidence-based discussion of therapy implementation for the various IV nutrient strategies presented. These will be set in the context of their many years experience in managing IV cases.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
This session is designed for clinicians currently practicing Age Management Medicine either full or part time who would benefit from in depth, interactive discussions of cases involving various areas and clinical aspects of Age Management Medicine. This session will not include didactic lecture but focus exclusively on case presentations and interactive discussions. Presenters will be asked to provide a basic SOAP Note history of the patient case, and work through initial laboratory assessments, laboratory results, possible diagnoses, and development of an individual treatment plan of action.
7:00 AM - 7:45 AM
Forget What You Know About Probiotics!
Presented by Kiran Krishnan
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by MegaSpore Biotic
8:00 AM - 8:45 AM
Healthy Longevity Precision Medicine Poster Child & The Complex Case
Francisco Carreño, Ph.D.
Exercise Physiologist, Comite Center for Precision Medicine, New York, NY
Lecture Description:
Aging is inevitable. Aging optimally requires proactivity, personalization, and precision. In this advanced precision medicine case study, meet a male patient whose total health, at 81 years of age, rivals his 60-year-old self. The lecture explores how data from multiple precision health assessment tools—metabolomics, genomics, telomere biology, microbiology, and more—can be integrated, interpreted, and translated into an actionable plan for healthy longevity.
8:45 AM - 9:30 AM
Precision Medicine, Hormone Optimization & the Complex Case
L. Amma Brown, PA-C, MPT
Physician Assistant, Comite Center for Precision Medicine, New York, NY
Lecture Description:
This advanced precision medicine case involves a 41-year-old female presenting with menometrorrhagia, hot flushes, weight gain, biomarkers indicative of perimenopause, impaired carbohydrate metabolism, and a family history of cancer, diabetes, heart disease, hypertension, and liver disease. Our precision intervention involved lifestyle modifications, medications, and supplements to manage perimenopause and reverse a chronic disease trajectory at the cellular level, decades before symptoms.
9:30 AM - 10:15 AM
Flexible Dosing of Peptides in Complex Patient Cases
George C. Shapiro, M.D., FACC
Adjunct Assistant Professor Clinical Medicine, New York Medical College, Valhalla, NY
Founding Partner, Cenegenics, New York City
Member, AMMG Conference Planning Committee
Lecture Description:
This talk will explore several patients who experienced restrictions and complications with several areas of traditional age management medicine. In particular, the discussion will be centered around patients who had limitations that prevented them from using traditional medications and how new peptide therapies allowed the flexible and precise dosing to address these limitations. The talk will be centered around alternatives and additives to traditional testosterone replacement, PDE5 inhibitors and sexual function medications, growth hormone alternatives, and nueroprotective treatments. It will involve four specific patient cases to gain insights into the new options which are available and culminate in a question and answer session to help physicians with their own difficult cases.
10:15 AM - 10:30 AM
Break
10:30 AM - 11:15 AM
An Integrative Nutrition Approach to Chronic Inflammation in the Complex Cancer Patient
Mark N. Mead, MSc
Nutrition Educator & Integrative Medicine Research Consultant, Carolina Center for Integrative Medicine, Raleigh, NC; Integrative Cancer Support Services, Plum Spring Clinic, Chapel Hill, NC; Institute for Integrative Cancer Research & Education, Skokie, IL
Editorial Board Member, Integrative Cancer Therapies
Freelance Health Writer & Medical Editor
Lecture Description:
This lecture uses case studies to explore the pivotal role of chronic inflammation (and related metabolic and physiologic issues) in the treatment and management of older cancer patients. Intravenous vitamin C therapy figures in prominently here, as does targeted nutritional and botanical supplementation and even, in some cases, anti-angiogenic therapy such as copper chelation with Tetrathiomolybdate.
11:15 AM - 12:00 PM
Erectile Dysfunction: Exploring Multiple Etiologies and Treatment Strategies
Jeffry S. Life, M.D., Ph.D.
Clinic Physician, Apeiron, Charleston, WV
Board Certified, Family Medicine
Diplomate, American Board of Family Practitioners
Fellow, American Academy of Family Physicians
Lecture Description:
This case involves a 58-year-old male physician presenting with a 3-month history of erectile dysfunction which he attributes to low testosterone levels, an impending divorce, and career changes. Further history and laboratory findings reveal multiple potential causes of his ED that are also profoundly impacting his life in many ways. Treatment strategies that will reverse his ED and improve his overall health, wellbeing, and longevity will be discussed involving audience participation.
12:00 PM - 1:00 PM
Telomere Biology Today
Presented by Joseph Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
12:00 PM - 1:30 PM
Lunch Break
1:30 PM - 2:15 PM
When Brains Collide: The Intersection of Concussions and the Aging Brain
Michael Lewis, M.D., MPH, MBA, FACPM, FACN
Colonel (Retired), U.S. Army
President and Founder, Brain Health Education and Research Institute
Physician, Cenegenics, Washington, D.C.
Lecture Description:
Over 3 million head injuries occur each year and millions of people are living with consequences of those injuries. Using a case study format, Dr. Michael Lewis will help the audience understand the role concussions can play in the aging brain, what initial laboratory and diagnostic assessments should be considered, the development of an individual treatment plan of action to include nutritional support, and how the interplay of neurotropic hormones can influence the outcome of therapy.
2:15 PM - 3:00 PM
Fibromyalgia and Metallothionein Dysfunction
Dan C. Purser, M.D
Medical Director
Physician, Clinical Practice, Provo, UT
Research Assistant to Nabil Gemayel, M.D. (Pituitary Endocrinology and Cardiology) USC Keck School of Medicine
President, Professional Nutraceutical Design
Lecture Description:
Recent amazing groundbreaking research has shown that fibromyalgia symptoms may be caused by excess non-ceruloplasmin bound copper (i.e. hypercuprosis), while the cause of hypercuprosis has been undetermined (other than some genetic causes), Dr. Purser determined that the root cause of fibromyalgia is most likely a metallothionein dysfunction. His soon to be published study confirms this and he goes through proofing, then a patient case example, leaving you with an understanding that fibromyalgia can be easily treated with natural metallothionein supporting supplements that will almost always resolve the fibromyalgia.
2:30 PM - 7:30 PM
Exhibits Open
3:00 PM - 3:45 PM
Break / Visit Exhibits
3:45 PM - 4:30 PM
Significantly Elevated Homocysteine Levels: Exploring Methylation Pathways and Treatment Strategies
Bhavesh K. Patel, M.D.
Founder and CEO, Cenegenics, Chicago, IL
Lecture Description:
Abnormally high homocysteine has been associated with significantly increased risk of dementia and heart disease, most likely due to its effect on the health of arteries. While many studies have been mixed regarding its cardiovascular interventional value, optimal values and challenges with treatment have confounded the results. However, high homocysteine levels can be a sign of much more insidious problems with the methionine-homocysteine pathways that are responsible for neurotransmitter production, methylation of DNA, detoxification and glutathione synthesis. Solving the riddle requires consideration of nutritional, physiologic and genetic factors, as well as an understanding of the underlying pathways. We’ll cover the symptoms and biochemical markers relevant to this pathway, as well as treatment strategies.
4:30 PM - 5:30 PM
MTHFR and Other Genetic Issues: A Cause for Unexplained Hypogonadism?
Dan C. Purser, M.D
Medical Director
Physician, Clinical Practice, Provo, UT
Research Assistant to Nabil Gemayel, M.D. (Pituitary Endocrinology and Cardiology) USC Keck School of Medicine
President, Professional Nutraceutical Design
Lecture Description:
After years of pituitary endocrinology research, it became clear that many male (and female) patients who presented had hypotestosteronism and/or hypogonadism (i.e. in women this also presented as ovarian insufficiency of unknown etiology) of unexplained etiology (not primary or secondary) (50% or more of the population who presented). When repeated intracellular (Spectracell) vitamin deficiencies were noted and then found to be very similar across a significant percentage of the population, an underlying cause was sought. Dietary and nutritional issues were examined but were excluded as diets were felt to be too variable to be the answer. The vitamin deficiencies discovered were very similar. What were the most common deficiencies noted? B12, pantothenate, and folate deficiencies, all somewhat difficult to amend with the usual therapy. The team then looked at MTHFR as a genetic condition that could lead to this kind of resistant deficiency. All but two of the patients (out of more than 300) were either heterozygous (carrying one of the errors) or homozygous (carrying two of the errors). Fatigue that was severe in nature was also the most common complaint. Conclusion: These patients were then treated aggressively with complex vitamin regimens appropriate for MTHFR. The treatment was based on the belief that if these patients had the deficiencies corrected, their testosterone levels should approve accordingly. Most had significant improvement in testosterone levels, libido,
fatigue, and quality of life. This lecture is designed to review the scientific literature on causes of hypogonadism and MTHFR and subsequently review case studies and treatment plans designed to get patients feeling better and greatly improving their quality of life.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
In response to attendee requests for information on aesthetic protocols and treatments which are office based and can be done by non-board certified Age Management Clinicians either full time or as an adjunct to their existing practice, AMMG presents this track in conjunction with the American Academy of Microneedling. The decision not to accredit this track was made so that attendees could be provided with business tools as well as the science and medical information necessary to implement these procedures. The goal is not to make this track commercial but to give speakers in this niche area the leverage to openly discuss procedures and answer questions that could be severely restricted in an accredited environment.
7:00 AM - 7:45 AM
Forget What You Know About Probiotics!
Presented by Kiran Krishnan
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by MegaSpore Biotic
8:00 AM - 9:00 AM
Laser Compliance Made Simple
John Cumiskey, D.C., CLSO
Certified Laser Safety Officer and Instructor, Co-Owner, Integrated Laser Solutions, LLC, Phoenix, AZ
Lecture Description:
This course will address laser compliance as it relates to medical and cosmetic lasers. It will classify laser compliance into two parts—laser safety and laser science—and the correlation between the two. The elements of laser safety and laser science will be highlighted as they relate to the medical or cosmetic laser operator. Laser Safety Officer rules and regulations as mandated by the American National Standards Institute and the Occupational Safety and Health Administration will be discussed. Examples will be given regarding the subjects that are included in basic laser science including basic laser physics and tissue interaction, as an example. The misconceptions on the requirements for Laser Science and Laser Safety will be illuminated. Examples and suggestions of how simple it is to become laser safety compliant are given. And finally, a brief mach course in laser science and laser safety will be conducted to allow attendees to understand the need for laser compliance.
9:00 AM - 10:00 AM
PRP Used with Fillers
Charles Runels, M.D.
Founder, American Cosmetic Cellular Medicine Association
Founder, Runels Center for Lifelong Health
Lecture Description:
Platelet-Rich plasma (PRP) has been used for over 10 years in the areas of orthopedics, oral surgery, & wound care. These same tissue healing strategies are now increasingly being used for the treatment of facial cosmetics and for the relief of sexual dysfunction. Dr. Runels is an innovator of PRP techniques to improve facial aesthetics as well as sexual function in men & women and will review the current literature and offer a preview of what’s coming.
10:00 AM - 10:15 AM
Break
10:15 AM - 11:15 AM
Human Adipose Derived Stem Cells (hADSCs) and Their Role in Healing and Skin Rejuvenation
Jordan R. Plews, Ph.D.
Chief Scientific Officer & Co-Founder, Xytogen Biotech
Lecture Description:
Human stem cells hold a lot of potential, but many of the advancements made in the last 10 years have not made it beyond the academic laboratory. This presentation reviews human stem cells, including pluripotent and mesenchymal stem cells, with specific emphasis on adipose derived stem cells (ADSCs) and their potential for healing and rejuvenating the skin. The proteins produced by mesenchymal stem cells, their role in the natural healing process of the skin, and the results from their topical application will also be discussed.
11:15 AM - 12:00 PM
Fat Grafting Outside the Box
Grant A. Fairbanks, M.D.
Founder, Fairbanks Plastic Surgery
Adjunct Assistant Professor in Surgery, University of Utah School of Medicine
Faculty, AAEG
Lecture Description:
Fat grafting has become significantly important in plastic surgery. Traditional uses were mainly for reconstruction of tissue volume loss. This has expanded to aesthetic cases. With better understanding, fat grafting is being used to improve tissue quality to include scar. It is suggested that adipose derived stem cells play an important role in the repair and regeneration of acute and chronically damaged tissues. Indications for fat grafting is expanding as demonstrated in this presentation.
12:00 PM - 1:00 PM
Telomere Biology Today
Presented by Joseph Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
12:00 PM - 1:30 PM
Lunch Break
1:30 PM - 2:30 PM
Microneedling with Hands-on Procedure Demonstration
Marie Piantino, L.E.
President, Aesthetic Education Group LLC
Founder, American Academy of Medical Microneedling
Nadia Bixler, L.E.I.
Owner, Halo Aesthetics Essentials, Boise, ID
Instructor, North West Laser Institute, Meridian, ID
Lecture Description:
Microneedling, CIT (collagen induction therapy) or vertical needling is a method of using an automatic device to perforate the tissue on the face and/or body. Tiny “micro” needles are used to create microchannels in the tissue which start a controlled wound healing action. This healing action is a natural process the body goes through after injury. Microneedling creates hundreds of thousands of microchannels in the dermas which heal themselves over the next several weeks. These tiny perforations also aid in product absorption, therefore peptides, hyaluronic acids & PRP (Platelet Rich Plasma) is topically applied during the microneedling process. Microneedling is gaining popularity in the medical aesthetic field because it can treat a variety of skin indications, and it is a high profit, non-invasive procedure that can be delegated to a nurse, MA or aesthetician.
2:30 PM - 7:30 PM
Exhibits Open
2:30 PM - 3:15 PM
Light Emitting Diodes: Fact or Fiction
Bertica M. Rubio, M.D.
Medical Director, Antiaging Regenerative Medicine Clinic, Redlands, CA
Medical Advisor, Rejuvenate Image Restoration, Refine and AQ Skin Solutions
Lecture Description:
LED or Light Emitting Diodes was first used in a NASA program for healing. How do we choose the right equipment and what are the key factors to look for? What do we use it for and what are the protocols for each treatment? Does price reflect quality? What wavelengths are needed and how many photons per square centimeter? All these questions will be answered in this lecture, as LED is rapidly becoming a vital part of the aesthetic menu and is an inexpensive addition to the physician office based protocols.
3:15 PM - 3:45 PM
Break / Visit Exhibits
3:45 PM - 4:45 PM
Microneedling: Amplifying Results with Radiofrequency Energy
H. William Song, M.D.
Founder and CEO, Omni Aesthetics, Oakland, NJ
Lecture Description:
Creating a controlled injury to activate the healing cascade is the basis behind most of the non-surgical skin treatments in aesthetic medicine. The microneedling procedure is a very popular way of utilizing this concept because of the relatively low cost and rapid recovery time. The down side is the need for multiple treatments and a long lag time between receiving the treatment and seeing results. Fractionated laser treatments are available for those seeking faster and more robust results. Unfortunately, the cost, risks and down time associated with a laser makes it a less attractive option for most clinicians. Combined microneedling / radiofrequency devices are now available to bridge the gap between these approaches. Dr. H. William Song will discuss the mechanism of action of microneedling and radiofrequency and explain how this combination can be a safe and very effective way to amplify the results for common conditions like skin laxity and acne scars.
4:45 PM - 5:30 PM
New Appeal of Private Label Brands
Sheila Malmanis, L.E.
President, MS Skintechnical, Inc., Phoenix, AZ
Lecture Description:
This informative lecture will introduce the multiple facets as to why physicians and spas are moving towards branding themselves through their own product line. Learn how the growth of private label has surpassed most premium brands in the medical aesthetic products market. Making the right choice and knowing the right questions to ask when researching a manufacturer or compounding pharmacy, knowing the percentages of active ingredients required when making claims, and knowing where to look for sources to research packaging are key to marketing your brand to make it successful.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
It is evident that the traditional approaches to Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD) are not working. Just look at the Sunday sports page or listen to the American Heroes Network. We are losing more and more people every day to the devastating effects of depression, anger, rage and suicide. So, what is the medical community really doing, if anything? In 2004, Dr. Mark Gordon started working on the premise that trauma to the head and/or body can cause disruption of neurosteroid and hormone production via chemical pathways. Additionally, trauma creates an inflammatory environment in the body that affects the chemistry in the brain. The combination of hormonal disruption and inflammation are at the root cause of impairment in cognition and behavior. This track will take you through the medical literature to disclose the cause and effects of TBI on brain functioning. Case reviews will be presented showing laboratory testing, interpretation, treatment and outcomes. Dr. Mark Gordon is faculty for all sessions in this track.
In conjunction with the Warrior Angels Foundation, a 501(c)(3) non-profit Organization
A portion of the proceeds from this course will be donated to the Warrior Angels Foundation as they work towards their goal of providing personalized assessment and treatment for U.S. Military Service Members and Veterans who have sustained Traumatic Brain Injury (TBI) while in the line of duty.
7:00 AM - 7:45 AM
Forget What You Know About Probiotics!
Presented by Kiran Krishnan
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by MegaSpore Biotic
8:00 AM - 8:30 AM
An Introduction to Traumatic Brain Injury
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
A 30-minute overview of trauma, inflammation, and how it impacts the cognitive and emotional functionality of the brain.
8:30 AM - 9:30 AM
Neurology, Neuropathology and Neuroendocrinology in Traumatic Brain Injury
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
60-minute discussion based upon literature about the specific cellular and biochemical cascades that are initiated by neuro-trauma. Expanding discussion on the indolent and stealth progression of the initial injury (primary) and the years of damage produced by the secondary injury.
9:30 AM - 10:15 AM
The Laboratory of Traumatic Brain Injury
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The assessment of neurotrauma using trophic, neurosteroids, and neuroactive steroids as markers for hormonal deficiencies that are caused by both the primary and secondary injuries associated with neurotrauma (TBI). The literature supported view that the “standard reference” ranges and “normal” reference ranges are not relative to the patient. Interpretation of the lab results using the Median Theory of optimal levels.
10:15 AM - 10:30 AM
Break
10:30 AM - 11:30 AM
Traumatic Brain Injury and Neurobehavior
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The impact of neurosteroid deficiencies on both personality and mental abilities is clearly discussed in peer-reviewed articles. Those same articles provide support for mood and anxiety disorders developing from loss of the regulatory effects of many of the neurosteroids that are produced in the brain.
11:30 AM - 12:00 PM
Supplementation for Traumatic Brain Injury - Part I
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The major impact of trauma is the production of secondary injury precipitated by free radicles and oxidative stress. The use of specific anti-oxidants and the regeneration of the glutathione system in the brain can help to regain a Neuro-Permissive Environment that can allow for cellular repair and regeneration.
12:00 PM - 1:00 PM
Telomere Biology Today
Presented by Joseph Raffaele, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by T.A. Sciences
12:00 PM - 1:30 PM
Lunch Break
1:30 PM - 2:30 PM
Supplementation for Traumatic Brain Injury - Part II
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
Continuation of the 5th lecture with specific application and treatment of traumatic brain injury. A number of cases will be discussed.
2:30 PM - 7:30 PM
Exhibits Open
2:30 PM - 3:30 PM
Case Studies - Part I
Dr. Mark Gordon is faculty for all sessions in this track.
Lecture Description:
15 comprehensive cases will be dissected and presented with attendees’ participation as a means of consolidating the information that will be shared throughout the day.
3:30 PM - 4:10 PM
Break / Visit Exhibits
4:10 PM - 5:30 PM
Case Studies - Part II
Dr. Mark Gordon is faculty for all sessions in this track.
Lecture Description:
Continuation of the cases with attendee participation and Q & A. The goal of these cases is to allow the audience an opportunity to work out with the lecturer the initial evaluation of the patient, laboratory testing, interpretation of the test results, and selection of an optimal treatment protocol.
5:30 PM - 7:00 PM
AMMG Welcome Reception
Open to all conference attendees, spouses and guests
Held in Conference Networking and Exhibits Center
7:00 AM - 7:45 AM
How to Build a Strong Age Management Business by Implementing Medical Weight Loss Into Your Practice
Presented by Kimball Lundahl, D.C.
Open to all attendees and includes a complimentary breakfast
Non-CME breakfast symposium sponsored by Healthy Habits
8:00 AM - 8:05 AM
Opening Remarks
Derrick M. DeSilva, Jr., M.D.
Chairman, AMMG Conference Planning Committee
Senior Attending Staff, Dept. of Medicine, Raritan Bay Medical Center, Perth Amboy, NJ
Teaching Faculty, JFK Medical Center, Edison, NJ
8:05 AM - 8:55 AM
Historical Progression and Progress of Age Management Medicine: Where Are We Today? An Update 10 Years Later
Derrick M. DeSilva, Jr., M.D.
Chairman, AMMG Conference Planning Committee
Senior Attending Staff, Dept. of Medicine, Raritan Bay Medical Center, Perth Amboy, NJ
Teaching Faculty, JFK Medical Center, Edison, NJ
Lecture Description:
A look into my crystal ball at the next 10 years in age management medicine shows great promise. The promise of a better understanding of the aging process and the new technologies that will allow us to live a better quality of life. Yes, I see organs being grown and transplanted curing diabetics. Engineering hearts that are immunogically identical to the recipient and taking heart disease out of the #1 spot for death. Perhaps a pill that will clean out our arteries of plaque without all the side effects that actually increase morbidity. I also see the simpler technologies coming back. For example, a deeper understanding of how sugar kills us and hoping that we finally get IT. The “getting IT” part about sugar will likely take another three to four decades until we find a way to transplant “brains.” THE FUTURE IS BRIGHT.
8:55 AM - 9:55 AM
The Future: Precision Medicine Today
Florence Comite, M.D.
CEO & Founder, Comite Center for Precision Medicine, New York, NY
Member, AMMG Conference Planning Committee
Lecture Description:
Imagine a world where you can detect, predict and reverse diseases of aging, decades before symptoms emerged; a world where proactive health interventions are precisely tailored to each patient’s distinct metabolism, hormonal profile, genetics, personal and family history, lifestyle, and environment. From disease care to health care—finally! That world is here. Precision Medicine is the future of medicine now. This lecture explores the power and practical application of precision medicine in the clinic. Understand how the physician can employ the best traditional medicine tools with cutting-edge health technologies, including genomics and metabolomics, to generate a precise understanding of each patient at the cellular level, and develop an actionable plan to reverse disease and optimize healthy longevity.
9:55 AM - 10:35 AM
Break / Visit Exhibits
10:35 AM - 11:15 AM
Precision Medicine at Geisinger: Experience in Identification of Inherited, Early Onset Cancer and Cardiovascular Disease in a Learning Healthcare System
David H. Ledbetter, Ph.D., FACMG
Executive Vice President & Chief Scientific Officer, Geisinger Health System, Danville, PA
Lecture Description:
Geisinger Health System is a large, integrated healthcare delivery system in Pennsylvania and New Jersey with comprehensive electronic health information going back to 1996. A precision medicine program, including a DNA biobank and genomic analyses, was initiated in 2007 to determine when and how genomic information can identify disease risk prior to clinical presentation and allow earlier detection and treatment or prevention of disease. To date, our MyCode Community Health Initiative has recruited and consented >130,000 patient-participants. In partnership with the Regeneron Genetics Center in New York, we have completed whole exome sequencing on over 50,000 of these participants. Using guidelines from the American College of Medical Genetics, we identify 3.5% of adults in our population with clear disease-causing mutations in genes known to cause early-onset cancer (BRCA breast/ovarian cancer, Lynch syndrome colon cancer) or cardiovascular diseases (familial hypercholesterolemia or FH; hypertophic cardiomyopathies, cardia arrhythmias). We have provided clinical genetics laboratory reports and genetic counseling to >200 participants and to their primary care providers with very positive acceptance by both groups. Although our experience is early, we anticipate that this population screening approach will identify a large percentage of inherited cancer and cardiovascular disease risk and significantly improve health outcomes for these individuals and their family members.
11:15 AM - 12:15 PM
Precision Pain Management: A Personalized Approach to Stem Cell Therapy
Drew DeMann, D.C., CCSP, MA, FNP, RMSK, GCSRT
Director, Board Certified Pain Management, Manhattan Medicine, New York, NY
Lecture Description:
Orthopedic pain management has traditionally been focused on “the management of pain” rather than providing patients with real solutions to their individual problems. Patients are generally treated with generic care plans centered around symptom management rather than restoring health and function. The result has been disastrous. More patients today rely on opiate pain medications than ever before. More patients are turning to surgical options, some of which unfortunately often lead to more pain and loss of function. A breakthrough came with simultaneous advancements in both high-resolution ultrasound imaging and stem cell therapies. New point of care ultrasound imaging with resolutions 10x greater than current MRI technology can often identify elusive sources of acute or chronic pain. This very same imaging can then be used to guide treatment in real time with pinpoint accuracy. Unrelated advancements in stem cell treatment and regenerative medicine now give the clinician something that can be administered under ultrasound guidance to actually repair the root cause of pain, not just suppress it. Regenerative therapies harness the body’s own inherent capabilities using stem cells to heal damaged or injured tissue relieving symptoms permanently. This presentation will review some of these new techniques in precision pain management, discussing both advancements in diagnosis and management with regenerative stem cell therapies.
12:15 PM - 1:30 PM
Lunch Break / Visit Exhibits
12:15 PM - 1:15 PM
Sub-Cutaneous Hormone Pellet Therapy: Alternative Medicine and An Alternative to “Bad Medicine” and a “Fascinating” Way to Help Patients
Presented by Gary S. Donovitz, M.D.
Open to all attendees and includes a complimentary lunch
Non-CME symposium sponsored by BioTE Medical
1:30 PM - 2:15 PM
Nitric Oxide Biochemistry and Physiology
David Lefer, Ph.D.
Professor, Department of Pharmacology, LSU Health Sciences Center, New Orleans, LA
Director, LSU Cardiovascular Center of Excellence, LSU Health Sciences Center
Lecture Description:
Nitric oxide (NO) is generated in the circulation from the precursor, L-arginine, via the actions of endothelial nitric oxide synthase (eNOS). Nitric oxide exerts a number of protective effects on the heart and circulation including: antioxidant, anti-inflammatory, vasodilatory, and anti-platelet. These actions are required to maintain cardiovascular homeostasis and when NO bioavailability is reduced cardiovascular disease progression occurs. Aging and cardiovascular diseases are characterized by reductions in NO levels and reductions in nitric oxide are thought to contribute to and cardiovascular diseases. Current preclinical and clinical research is aimed at the investigation of novel nitric oxide based therapies to treat cardiovascular diseases including acute myocardial infarction, heart failure, hypertension, and stroke. Development of nitric oxide based therapies is very difficult due to the very short half-life (i.e., 1-2 seconds) of nitric oxide in biological systems. Nitric oxide is converted to stable metabolites that can be stored in the blood and tissues and utilized as an alternate source of nitric oxide. Nitrite is a stable nitric oxide metabolite that is generated with nitric oxide reacts with oxygen in the circulation and is then stored in the blood and tissues. Nitrite can be converted back into nitric oxide under conditions of hypoxia or tissue ischemia to exert protective effects. We have extensively investigated the cardioprotective actions of nitrite in
experimental models of myocardial infarction and heart failure. Our data indicate that nitrite ameliorates the severity of acute myocardial infarction and heart failure. The protective actions of nitrite appear to be a result of cytoprotective actions mediated by nitric oxide generated from nitrite. Data will be presented describing the biochemistry of nitric oxide, the physiological actions of nitric oxide, and the cardioprotective effects of nitric oxide based therapeutics.
2:15 PM - 3:15 PM
Hypertension, Inflammation and Nitric Oxide
Nathan S. Bryan, Ph.D.
Professor, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX
Lecture Description:
Loss of nitric oxide (NO) production is recognized as the earliest event in the onset and progression of cardiovascular disease. Hypertension and inflammation are hallmarks of insufficient nitric oxide production and the primary risk factors for the development of cardiovascular disease. Restoring production of nitric oxide can inhibit sources of inflammation, reduce markers of inflammation, lower blood pressure and enhance vascular integrity. This lecture will discuss mechanisms of vascular inflammation and nitric oxide production and the clinical consequences of loss of NO production. New therapeutic strategies will be introduced including diet and lifestyle changes to enhance NO production.
3:15 PM - 3:45 PM
Break / Visit Exhibits
3:45 PM - 4:40 PM
CBD and the Brain
Michael Lewis, M.D., MPH, MBA, FACPM, FACN
Colonel (Retired), U.S. Army
President and Founder, Brain Health Education and Research Institute
Physician, Cenegenics, Washington, D.C.
Lecture Description:
Recently, there is much renewed interest in industrial hemp-derived cannabidiol, or CBD. Seventeen years ago, a Nobel prize winning neuroscientist at the National Institutes of Health filed for a patent describing CBD oil as a nonpsychoactive neuroprotectant and antioxidant. Dr. Michael Lewis will describe the patent that has application in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurogenerative diseases such Alzheimer's and Parkinson's diseases. Additionally, he will discuss his personal clinical experience with TBI patients and the use of CBD particularly for anxiety.
4:40 PM - 5:30 PM
Your Brain, Your Hormones: New Hope for Those at Risk
Gary Donovitz, M.D., FACOG, FRSM
Founder and CEO, BioTE Medical, Irving, TX
Founder and President, Institute for Hormonal Balance
Lecture Description:
As your patients age the brain begins to suffer cognitive decline and loss of brain cells. The result can be mild cognitive decline, Alzheimer's disease, Parkinson's disease, and other neurologic ailments. In addition, our veterans are suffering increasing PTSD from TBI and the suicide rate is astounding. Is Big Pharma helping or hurting? Is hormone optimization the unknown underutilized prevention and therapy? This review will be both provocative and hopefully change your practice patterns.
7:00 AM - 7:45 AM
How to Choose a Compounding Pharmacy
Presented by Joe Grasela, R.Ph.
Open to all attendees and includes a complimentary breakfast
Non-CME symposium sponsored by University Compounding Pharmacy
8:00 AM - 8:45 AM
A New Look at PCOS and Insulin Resistance: A Functional Approach to Differential Diagnosis and Treatment
Rebecca R. Murray, APRN, FNP-BC, CDE
Endocrine Nurse Practitioner, Institute for Hormonal Balance, Orlando, FL
Medical Director, Ward-Murray HealthCare Consulting, Groton, CT
Scientific Advisory Board, Designs for Health
Lecture Description:
Symptoms associated with menstrual dysfunction are the number one reason for visits to a gynecological office and Polycystic Ovary Syndrome is the number one endocrine problem in women of childbearing age. The most common and accepted treatment is that of NSAIDS and/or birth control pills, neither of which solve the problem. The purpose of this presentation is to review the physiology of the functional abnormalities that result in the symptoms of PMS, dysmenorrhea, menorrhagia, oligomenorrhea, and amenorrhea/infertility and to discuss the tools available to us for an in-depth work-up and individualized treatment plan. Differential diagnoses will be reviewed in terms of the etiology of insulin resistance, defects in insulin signaling, enzymatic defects, and autoimmunity that can result in "premature ovarian failure".
8:45 AM - 9:30 AM
Extracorpeal Shockwave Therapy, a Cure for Erectile Dysfunction
Richard Gaines, M.D.
CMO, Sexual MD Solutions, Aventura, FL
CMO, AAG HealthGAINS, Aventura, FL
Lecture Description:
Sexual dysfunction in men is a growing problem in which Big Pharma is making billions without getting to the root of the issue. However, there’s a potential cure for ED that’s been in Europe for 15 years called extracorpeal shockwave therapy. This is a painless and non-invasive in-office procedure that is proven effective by treating the root cause of the issue.
9:30 AM - 10:00 AM
Break / Visit Exhibits
10:00 AM - 11:00 AM
Erectile Dysfunction: Causation and Clinical Treatment
Kathryn Retzler, N.D.
HormoneSynergy Clinic, Portland, OR
Lecture Description:
This lecture will cover the pathophysiology of ED including one common cause/contributing factor most physicians do not know. Screening questionnaires will be provided and all available treatment options including dosages will be discussed.
11:00 AM - 12:00 PM
What’s New and What’s Known: Impact of the Microbiome on Cardiometabolic Disease
Todd R. LePine, M.D.
Private Practice Internal Medicine, Stockbridge, MA
Staff Physician, UltraWellness Center, Lenox, MA
Lecture Description:
Research has indicated that altered gut microbial composition may be a primary contributor to increased global incidence of metabolic disorders. Reduced microbial diversity and abundance has been implicated in immune reactions and cardiometabolic disease. The gut microbiota plays a number of important roles including digestion, metabolism, extraction of nutrients, synthesis of vitamins, prevention against pathogen colonization, and modulation of the immune system. Early studies first supported a role for gut microbes in both affecting host energy metabolism and modulating lipid levels. An important clinical implication from studies on gut microbiota is how to leverage findings for therapeutic purposes. In this lecture we will review accepted and effective clinical applications and treatments that can help to modulate the gut microbiome and its impact on the risk for cardiometabolic disease.
12:00 PM - 1:15 PM
Lunch Break / Visit Exhibits
1:15 PM - 2:00 PM
Optimizing Growth Hormone and Sex with Peptide Therapy
Edwin N. Lee, M.D., FACE
Assistant Professor of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL
Founder, Institute for Hormonal Balance
Member, AMMG Conference Planning Committee
Lecture Description:
Growth hormone is an essential hormone in lowering body fat, improving on lipids, keeping muscles healthy and improving on bone density. Adult growth hormone deficiency symptoms will be reviewed and the association of higher mortality with growth hormone deficiency. Unfortunately the treatment with recombinant human growth hormone is not covered under most insurance plans and is also expensive for most people to pay for in cash. There is an alternative to the expensive recombinant human growth hormone mostly commonly used for boosting IGF-1 and has the advantage of inducing all five of the hGH isoforms rather than just the one that is found in the synthetic form. CJC-1295, Ipamorelin and Teslomorelin are peptides that have been shown to help improve IGF-1 levels. Bremelanodtide PT141 will be discussed to help with sexual function in men and in women.
2:00 PM - 2:45 PM
The Thyroid, Adrenal, Pancreas Connection: A Synopsis of Metabolism, Energy, and Stress on the Human Body
Benjamin S. Gonzalez, M.D.
Medical Director, Atlantis Medical Wellness Center, Silver Spring, MD
Lecture Description:
Basic endocrine system review. Specific review of pancreas, thyroid and adrenal glands. Discuss the cortisol and insulin effects on the body. Review the difference between short term physical stress and long term physiological stress. Discuss the role of cortisol in obesity. Review the failure of the carbohydrate-insulin hypothesis as it relates to obesity. Discuss the role of insulin resistance in the aging process. Summarize the practical application of understanding the pancreas, thyroid and adrenal gland triad.
2:45 PM - 3:30 PM
Break / Visit Exhibits (exhibits close 4:00 pm)
3:30 PM - 4:15 PM
Estrogen Metabolism
Jennifer Pearlman, M.D., CCFP, NCMP, FAARM, ABAARM
Attending Staff Physician, Menopause Clinic, Mount Sinai Hospital, Toronto, Canada
Owner and Medical Director, Pearl MD Rejuvenation, Toronto, Canada
Lecture Description:
Estrogen metabolism is one of the most poorly understand and recognized area of human health yet has far reaching impact on health, risk of disease and cancer. Learn how to improve hormone health in your patients by augmenting the body's innate detoxification systems involved in estrogen metabolism that allow us to detoxify, inactivate and eliminate endogenous and exogenous estrogens as well as xenoestrogens. Lecture will cover innate detoxification, steroidogenic hormonal pathways, estrogen metabolism, genetic determinants of estrogen metabolism, epigenetic factors, environmental exposures, impaired estrogen metabolism, and clinical cases using a functional approach to optimize estrogen metabolism.
4:15 PM - 5:30 PM
Use of Low Dose Naltrexone and its Application to Inflammatory Bowel Disease, Cancer, and Autoimmune Diseases
Paul Battle, PA-C
Rocky Mountain Pediatric Orthopedics, Denver, CO
Lecture Description:
There are many applications for this drug. It has been used for 200 different autoimmune diseases, and now recent research in England has shown it to kill cancer cells. It has been used for cancer when patients have been told they have a fatal several month life expectancy and they have survived 10 years, i.e. pancreatic cancer.
8:00 AM - 9:00 AM
The Science of Growth Hormone Secretagogue Technology
Mark L. Gordon, M.D.
Medical Director, Millennium-TBI & The Millennium Health Centers, Encino, CA; CBS Studios;
USC, Keck School of Medicine, Department of Family Medicine, Los Angeles, CA
Medical Director of Education, Access Medical Laboratories, Jupiter, FL
Member, AMMG Conference Planning Committee
Life Member, AMMG
Lecture Description:
The recognition and acceptance of non-peptide, synthetic complexes as potent growth hormone (GH) secretogogues has been less than positive due to a number of perceived limitations. These perceptions were based upon our lack of scientific evidence to support the supposition that something other than a complex peptide, such as growth hormone releasing hormone (GHRH) could increase a hormone’s production. Additionally, we lacked the scientific knowledge about flexible receptors that could accept a broad range of chemical structures that would lead to the stimulated production or suppression of a hormone. Finally, we are starting to understand more about the complex influences that hormones, peptides, and amino acids have on the hypothalamic-pituitary axis. Firstly, past research data was based upon small test groups of individuals that were given large quantities of mixed amino acids designed to enhance GH production and release. Although many of these compounds demonstrated a measurable elevation in the GH/ insulin-like growth factor 1 (IGF-1) axis, many were also associated with osmotic diarrhea, making it a difficult pill to swallow. Secondly, delivery of amino acids by mouth has a poor bioavailability due to its destruction and inactivation by gastric acid. A large compensatory dose is then needed to correct for this diminished availability, thereby leading to the side-effect of diarrhea. Thirdly, since the action of a secretagogue is to increase the amplitude and duration
of intrinsic GH secretion, the normal regulatory or homeostatic mechanism (positive feedback and negative feedback) is preserved. When a secretagogue elevates the intrinsic production of GH above the body’s inherent set-point, Somatostatin release (also known as somatotrope release inhibiting factor (SRIF)) causes the suppression of intrinsic GH production. This, in turn, can lead to the waxing and waning of GH/IGF-1 levels, making it difficult to accurately assess the net effect. These issues have generated the majority of resistance to the use of secretagogue in healthy individuals with low GH, IGF-1, and insulin-like growth factor binding protein 3 (IGFBP-3) levels. This presentation will provide current, evidence-based scientific literature, and clinical results to support the use of a secretagogue as a logical “first step” approach to the treatment of GH deficiency in healthy individuals.
9:00 AM - 10:00 AM
The Role of Estrogen in the Uro-Genital Health of Postmenopausal Women: Physiology, Pathology and Practical Recommendations
Israel Yoles, M.D.
Chief Gynecologist, Central District of Clalit Health Services & Head of the Center for Women’s Health, Clalit Health Services, Israel
Certified Menopause Practitioner, North American Menopause Society (NCMP)
Lecture Description:
The vital role of estrogen on vaginal health and on the urinary tract, will be discussed. Physiological and functional effects of estrogen on vaginal mucosa and local vascularity, will be reviewed. Additionally, we will discuss Genitourinary Syndrome of Menopause caused by the drop in estrogen levels during the perimenopause and menopausal stages. This syndrome affects at least half of postmenopausal women but is often undertreated. The pathological symptoms and findings as well as treatment options will be discussed at length.
10:00 AM - 10:30 AM
Break
10:30 AM - 11:15 AM
Exercising is Medicine: Maximizing Patient Outcomes
J.R. Burgess, MS, CPT
CEO, Rejuv Medical, Waite Park, MN
Fitness Professional, Health and Wellness Coach
Lecture Description:
Exercise and proper nutrition is the foundation to all Functional Medicine and Anti-Aging treatments as well as a necessity for healing and preventing injures in patients. It is also one of the most difficult areas to train and teach our patients to do successfully. As we optimize body composition through increasing lean muscle mass while decreasing the fat mass, many of the hormone imbalances that are causing chronic disease can be eliminated. As specialists in our field, we need to have the tools to educate and train our patients on proper exercise and lifelong nutrition to maximize the healthy changes in the lives of our patients. As physicians we have the ability to influence our patients to make positive changes in their fitness and nutrition that will impact their clinical outcomes. We just need to implement those into our current practice models. With the uncertainty regarding the future of the healthcare system, physicians and private practices are looking for solutions during these fearful and uncertain economic times. There is fear that the Affordable Healthcare Act will make it difficult for private practices to survive, and for doctors to make the living they deserve. Facts are, with rising costs, reimbursements are sure to be cut. Fortunately there is a new cash-based model that doctors are implementing that can have both a positive financial outcome for your practice and provides a solution to rising health care costs by reducing obesity. The obesity epidemic
and the incidence of disease and injury have forced the need for a preventable, medically integrated, outcome based model of medical fitness. Today’s crisis leads to a new spectrum that will combat rising health care costs and lower reimbursements. It’s my focus along with several other affiliations such as the Medical Fitness Association to help bridge the gap between traditional treatments and long-term prevention.
11:15 AM - 12:00 PM
Exercise Prescription: A Precision Medicine Approach
Francisco Carreño, Ph.D.
Exercise Physiologist, Comite Center for Precision Medicine, New York, NY
Lecture Description:
Exercise is a critical element in the proactive prevention of many diseases of aging, as well as a treatment modality. A personalized plan precisely tailored to an individual’s unique genetic, metabolic, and phenotypic makeup contributes to optimum benefit. This lecture explores the mechanistic role of exercise to optimize healthy longevity, and the precise considerations necessary to customize exercise and nutrition interventions and therapies for disparate patients. A series of case studies will illustrate the practical application of precision exercise prescriptions in the clinic.
12:00 PM - 12:45 PM
Sarcopenic Obesity: Evidence-Based Exercise Strategies
Joseph F. Signorile, Ph.D.
Professor, Department of Kinesiology and Sport Sciences, University of Miami, Miami, FL
Lecture Description:
Part of the aging process in our industrialized world is an untenable condition known as sarcopenic obesity. Sarcopenic obesity can be thought of as having the “worst of both worlds.” The loss of muscle mass (sarcopenia), and the associated loss in function, has been reported for decades. However, the increase in fat mass has only recently been recognized as synergistic factor having an exponential negative effect on both physical function and metabolism in older persons. In fact, thanks to their loss of muscle mass and increase in adipose tissue, the “fat-frail” are at greater risk for metabolic syndrome, reduced independence and the probability of injurious falls. This lecture examines the prevalence of sarcopenic obesity in older persons living in industrialized societies. It also explores the spiraling effects which inactivity can have on this condition. And finally, the presentation explores the exercise and dietary interventions that may be used to effectively address this condition.
12:45 PM - 1:30 PM
The Therapeutic Potential of Nutritional Ketosis in Age Management
H. Douglas Woodford, M.D., FACOG
Clinical Director
Physician, Full Life Wellness Center, Florence, AL
Lecture Description:
The Low Carbohydrate/High Fat diet, producing the unique metabolic state of nutritional ketosis, is currently one of the most active areas of medical research. This lecture will help healthcare providers understand the epigenetic effects of keto-adaptation, how to achieve and maintain nutritional ketosis and explore effects of ketone metabolism on aging, metabolic disease, neurological disease and cancer. Aging: Beta-hydroxybutyrate has been shown to increase the lifespan of C. elegans up to 26%. It has also been shown to inhibit histone deacetylase and activate the genes encoding for oxidative stress resistance. Diabetes/Metabolic Syndrome: A recent Journal of Nutrition article published by 26 of the best MDs and PhDs in the field of nutrition reviewed 12 points of evidence supporting the ketogenic diet as the first approach in diabetes management. This evidence will be reviewed. Neurological disorders: The ketogenic diet has been used to treat seizures since the 1920s. This lecture will review some of the latest research on early Alzheimer’s reversal, treatment of brain trauma and Parkinson’s disease. Cancer: This lecture will review the effects of ketone metabolism on cancer cells and discuss cancer as a metabolic disease.
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